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Inhibition of the Keap1/Nrf2 Signaling Pathway Significantly Promotes the Progression of Type 1 Diabetes Mellitus
Type 1 diabetes mellitus (T1DM) is an autoimmune disease characterized by insulin deficiency due to pancreatic β-cell damage and leads to hyperglycemia. The precise molecular mechanisms of the etiology of T1DM are not completely understood. Oxidative stress and the antioxidant status of pancreatic β...
Autores principales: | Lou, Yanmei, Kong, Muyan, Li, Leyan, Hu, Yu, Zhai, Wenjun, Qi, Xiaoxiao, Liu, Zhongqiu, Wu, Jinjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884168/ https://www.ncbi.nlm.nih.gov/pubmed/33628382 http://dx.doi.org/10.1155/2021/7866720 |
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