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Recent Epidemiological Changes in Group B Streptococcus Among Pregnant Korean Women

BACKGROUND: Although group B Streptococcus (GBS) colonization rate among pregnant Korean women is lower than that among women from many Western countries, recent data show an upward trend. We investigated recent epidemiological changes in GBS among pregnant Korean women in terms of colonization rate...

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Autores principales: Choi, Seong Jin, Kang, Jieun, Uh, Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Laboratory Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884197/
https://www.ncbi.nlm.nih.gov/pubmed/33536356
http://dx.doi.org/10.3343/alm.2021.41.4.380
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author Choi, Seong Jin
Kang, Jieun
Uh, Young
author_facet Choi, Seong Jin
Kang, Jieun
Uh, Young
author_sort Choi, Seong Jin
collection PubMed
description BACKGROUND: Although group B Streptococcus (GBS) colonization rate among pregnant Korean women is lower than that among women from many Western countries, recent data show an upward trend. We investigated recent epidemiological changes in GBS among pregnant Korean women in terms of colonization rate, antimicrobial susceptibility, serotype, and resistance genotype. METHODS: Vaginal and anorectal swab specimens from 379 pregnant Korean women were cultured on Strep B Carrot Broth with GBS Detect (Hardy Diagnostics, USA), selective Todd-Hewitt broth (Becton Dickinson, USA), and Granada agar plate medium (Becton Dickinson). The antimicrobial susceptibility, serotypes, and macrolide-lincosamide-streptogramin B (MLS(B)) resistance genes of the GBS isolates were tested. RESULTS: The GBS colonization rate among pregnant Korean women was 19.8% (75/379). Colonization rates using Strep B Carrot Broth with GBS Detect, selective Todd-Hewitt broth, and Granada agar plate medium cultures were 19.5%, 19.3%, and 15.0%, respectively. Six pregnant women were colonized by non-beta-hemolytic GBS and were detected only in Strep B Carrot Broth with GBS Detect. Resistance rates of GBS to clindamycin, erythromycin, and tetracycline were 16.0%, 28.0%, and 42.7%, respectively. The most common GBS serotypes were V (22.7%), VIII (20.0%), and III (20.0%). The frequency of MLS(B) resistance geneserm(B) anderm(TR) were 63.6% and 36.4%, respectively. CONCLUSIONS: The GBS colonization rate among pregnant Korean women has risen to levels observed in Western countries. To accurately evaluate GBS epidemiology among pregnant Korean women, periodic studies in multiple centers, including primary clinics, are necessary.
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spelling pubmed-78841972021-07-01 Recent Epidemiological Changes in Group B Streptococcus Among Pregnant Korean Women Choi, Seong Jin Kang, Jieun Uh, Young Ann Lab Med Original Article BACKGROUND: Although group B Streptococcus (GBS) colonization rate among pregnant Korean women is lower than that among women from many Western countries, recent data show an upward trend. We investigated recent epidemiological changes in GBS among pregnant Korean women in terms of colonization rate, antimicrobial susceptibility, serotype, and resistance genotype. METHODS: Vaginal and anorectal swab specimens from 379 pregnant Korean women were cultured on Strep B Carrot Broth with GBS Detect (Hardy Diagnostics, USA), selective Todd-Hewitt broth (Becton Dickinson, USA), and Granada agar plate medium (Becton Dickinson). The antimicrobial susceptibility, serotypes, and macrolide-lincosamide-streptogramin B (MLS(B)) resistance genes of the GBS isolates were tested. RESULTS: The GBS colonization rate among pregnant Korean women was 19.8% (75/379). Colonization rates using Strep B Carrot Broth with GBS Detect, selective Todd-Hewitt broth, and Granada agar plate medium cultures were 19.5%, 19.3%, and 15.0%, respectively. Six pregnant women were colonized by non-beta-hemolytic GBS and were detected only in Strep B Carrot Broth with GBS Detect. Resistance rates of GBS to clindamycin, erythromycin, and tetracycline were 16.0%, 28.0%, and 42.7%, respectively. The most common GBS serotypes were V (22.7%), VIII (20.0%), and III (20.0%). The frequency of MLS(B) resistance geneserm(B) anderm(TR) were 63.6% and 36.4%, respectively. CONCLUSIONS: The GBS colonization rate among pregnant Korean women has risen to levels observed in Western countries. To accurately evaluate GBS epidemiology among pregnant Korean women, periodic studies in multiple centers, including primary clinics, are necessary. Korean Society for Laboratory Medicine 2021-07-01 2021-07-01 /pmc/articles/PMC7884197/ /pubmed/33536356 http://dx.doi.org/10.3343/alm.2021.41.4.380 Text en © Korean Society for Laboratory Medicine https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Choi, Seong Jin
Kang, Jieun
Uh, Young
Recent Epidemiological Changes in Group B Streptococcus Among Pregnant Korean Women
title Recent Epidemiological Changes in Group B Streptococcus Among Pregnant Korean Women
title_full Recent Epidemiological Changes in Group B Streptococcus Among Pregnant Korean Women
title_fullStr Recent Epidemiological Changes in Group B Streptococcus Among Pregnant Korean Women
title_full_unstemmed Recent Epidemiological Changes in Group B Streptococcus Among Pregnant Korean Women
title_short Recent Epidemiological Changes in Group B Streptococcus Among Pregnant Korean Women
title_sort recent epidemiological changes in group b streptococcus among pregnant korean women
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884197/
https://www.ncbi.nlm.nih.gov/pubmed/33536356
http://dx.doi.org/10.3343/alm.2021.41.4.380
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