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Identification of a conserved N‐terminal domain in the first module of ACV synthetases
The l‐δ‐(α‐aminoadipoyl)‐l‐cysteinyl‐d‐valine synthetase (ACVS) is a trimodular nonribosomal peptide synthetase (NRPS) that provides the peptide precursor for the synthesis of β‐lactams. The enzyme has been extensively characterized in terms of tripeptide formation and substrate specificity. The fir...
Autores principales: | Iacovelli, Riccardo, Mózsik, László, Bovenberg, Roel A.L., Driessen, Arnold J.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884236/ https://www.ncbi.nlm.nih.gov/pubmed/33449449 http://dx.doi.org/10.1002/mbo3.1145 |
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