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Identification of a conserved N‐terminal domain in the first module of ACV synthetases

The l‐δ‐(α‐aminoadipoyl)‐l‐cysteinyl‐d‐valine synthetase (ACVS) is a trimodular nonribosomal peptide synthetase (NRPS) that provides the peptide precursor for the synthesis of β‐lactams. The enzyme has been extensively characterized in terms of tripeptide formation and substrate specificity. The fir...

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Detalles Bibliográficos
Autores principales: Iacovelli, Riccardo, Mózsik, László, Bovenberg, Roel A.L., Driessen, Arnold J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884236/
https://www.ncbi.nlm.nih.gov/pubmed/33449449
http://dx.doi.org/10.1002/mbo3.1145

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