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Apurinic/Apyrimidinic Endonuclease 1 Restricts the Internalization of Bacteria Into Human Intestinal Epithelial Cells Through the Inhibition of Rac1

Pathogenic intestinal bacteria lead to significant disease in humans. Here we investigated the role of the multifunctional protein, Apurinic/apyrimidinic endonuclease 1 (APE1), in regulating the internalization of bacteria into the intestinal epithelium. Intestinal tumor-cell lines and primary human...

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Detalles Bibliográficos
Autores principales:	den Hartog, Gerco, Butcher, Lindsay D., Ablack, Amber L., Pace, Laura A., Ablack, Jailal N. G., Xiong, Richard, Das, Soumita, Stappenbeck, Thaddeus S., Eckmann, Lars, Ernst, Peter B., Crowe, Sheila E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884313/ https://www.ncbi.nlm.nih.gov/pubmed/33603730 http://dx.doi.org/10.3389/fimmu.2020.553994

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