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Role of MDA5 in regulating CXCL10 expression induced by TLR3 signaling in human rheumatoid fibroblast-like synoviocytes
C-X-C motif chemokine 10 (CXCL10) is an inflammatory chemokine and a key molecule in the pathogenesis of rheumatoid arthritis (RA). Melanoma differentiation-associated gene 5 (MDA5) is an RNA helicase that plays a role in innate immune and inflammatory reactions. The details of the regulatory mechan...
Autores principales: | Saruga, Tatsuro, Imaizumi, Tadaatsu, Kawaguchi, Shogo, Seya, Kazuhiko, Matsumiya, Tomoh, Sasaki, Eiji, Sasaki, Norihiro, Uesato, Ryoko, Ishibashi, Yasuyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884359/ https://www.ncbi.nlm.nih.gov/pubmed/33387195 http://dx.doi.org/10.1007/s11033-020-06069-z |
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