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A balance score between immune stimulatory and suppressive microenvironments identifies mediators of tumour immunity and predicts pan-cancer survival
BACKGROUND: The balance between immune-stimulatory and immune-suppressive mechanisms in the tumour microenvironment is associated with tumour rejection and can predict the efficacy of immune checkpoint-inhibition therapies. METHODS: We consider the observed differences between the transcriptional pr...
Autores principales: | Turan, Tolga, Kongpachith, Sarah, Halliwill, Kyle, Roelands, Jessica, Hendrickx, Wouter, Marincola, Francesco M., Hudson, Thomas J., Jacob, Howard J., Bedognetti, Davide, Samayoa, Josue, Ceccarelli, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884411/ https://www.ncbi.nlm.nih.gov/pubmed/33139798 http://dx.doi.org/10.1038/s41416-020-01145-4 |
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