UBE2S interacting with TRIM28 in the nucleus accelerates cell cycle by ubiquitination of p27 to promote hepatocellular carcinoma development

Genomic sequencing analysis of tumors provides potential molecular therapeutic targets for precision medicine. However, identifying a key driver gene or mutation that can be used for hepatocellular carcinoma (HCC) treatment remains difficult. Here, we performed whole-exome sequencing on genomic DNA...

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Detalles Bibliográficos
Autores principales: Zhang, Ren-Yu, Liu, Ze-Kun, Wei, Ding, Yong, Yu-Le, Lin, Peng, Li, Hao, Liu, Man, Zheng, Nai-Shan, Liu, Ke, Hu, Cai-Xia, Yang, Xiao-Zhen, Chen, Zhi-Nan, Bian, Huijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884418/
https://www.ncbi.nlm.nih.gov/pubmed/33589597
http://dx.doi.org/10.1038/s41392-020-00432-z

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