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Loss of the orphan nuclear receptor NR2F6 enhances CD8(+) T-cell memory via IFN-γ
Memory formation is a hallmark of T cell-mediated immunity, but how differentiation into either short-lived effector cells (SLECs, CD127(−)KLRG1(+)) or memory precursors cells (MPECs, CD127(+)KLRG1(−)) and subsequent regulation of long-term memory is adjusted is incompletely understood. Here, we sho...
Autores principales: | Jakic, Bojana, Olson, William J., Siegmund, Kerstin, Klepsch, Victoria, Kimpel, Janine, Labi, Verena, Zehn, Dietmar, Baier, Gottfried, Hermann-Kleiter, Natascha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884426/ https://www.ncbi.nlm.nih.gov/pubmed/33589606 http://dx.doi.org/10.1038/s41419-021-03470-9 |
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