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STIM2 Mediates Excessive Store-Operated Calcium Entry in Patient-Specific iPSC-Derived Neurons Modeling a Juvenile Form of Huntington's Disease

Huntington's disease (HD) is a severe autosomal-dominant neurodegenerative disorder caused by a mutation within a gene, encoding huntingtin protein. Here we have used the induced pluripotent stem cell technology to produce patient-specific terminally differentiated GABA-ergic medium spiny neuro...

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Detalles Bibliográficos
Autores principales:	Vigont, Vladimir A., Grekhnev, Dmitriy A., Lebedeva, Olga S., Gusev, Konstantin O., Volovikov, Egor A., Skopin, Anton Yu., Bogomazova, Alexandra N., Shuvalova, Lilia D., Zubkova, Olga A., Khomyakova, Ekaterina A., Glushankova, Lyubov N., Klyushnikov, Sergey A., Illarioshkin, Sergey N., Lagarkova, Maria A., Kaznacheyeva, Elena V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884642/ https://www.ncbi.nlm.nih.gov/pubmed/33604336 http://dx.doi.org/10.3389/fcell.2021.625231

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