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A randomised phase 2b study comparing the efficacy and safety of belotecan vs. topotecan as monotherapy for sensitive-relapsed small-cell lung cancer

BACKGROUND: This study compared the efficacy/safety of the camptothecin analogues belotecan and topotecan for sensitive-relapsed small-cell lung cancer (SCLC). METHODS: One-hundred-and-sixty-four patients were randomised (1:1) to receive five consecutive daily intravenous infusions of topotecan (1.5...

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Detalles Bibliográficos
Autores principales: Kang, Jin-Hyoung, Lee, Ki-Hyeong, Kim, Dong-Wan, Kim, Sang-We, Kim, Hye Ryun, Kim, Joo-Hang, Choi, Jin-Hyuk, An, Ho Jung, Kim, Jin-Soo, Jang, Joung-Soon, Kim, Bong-Seog, Kim, Heung Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884704/
https://www.ncbi.nlm.nih.gov/pubmed/33191408
http://dx.doi.org/10.1038/s41416-020-01055-5