Synthesis and Preliminary Evaluation of a Novel (18)F-Labeled 2-Nitroimidazole Derivative for Hypoxia Imaging

OBJECTIVE: Hypoxia is prevalent in tumors and plays a pivotal role in resistance to chemoradiotherapy. (18)F-MISO ((18)F-labeled fluoromisonidazole) is currently the preferred choice of PET hypoxia tracers in clinical practice, but has severe disadvantages involving complex labeling methods and low...

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Detalles Bibliográficos
Autores principales: Lu, Jing, Zhang, Chi, Yang, Xi, Yao, Xi-Juan, Zhang, Qun, Sun, Xin-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884749/
https://www.ncbi.nlm.nih.gov/pubmed/33604284
http://dx.doi.org/10.3389/fonc.2020.572097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884749/
https://www.ncbi.nlm.nih.gov/pubmed/33604284
http://dx.doi.org/10.3389/fonc.2020.572097

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