Cargando…

Synthesis and Preliminary Evaluation of a Novel (18)F-Labeled 2-Nitroimidazole Derivative for Hypoxia Imaging

OBJECTIVE: Hypoxia is prevalent in tumors and plays a pivotal role in resistance to chemoradiotherapy. (18)F-MISO ((18)F-labeled fluoromisonidazole) is currently the preferred choice of PET hypoxia tracers in clinical practice, but has severe disadvantages involving complex labeling methods and low...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Jing, Zhang, Chi, Yang, Xi, Yao, Xi-Juan, Zhang, Qun, Sun, Xin-Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884749/ https://www.ncbi.nlm.nih.gov/pubmed/33604284 http://dx.doi.org/10.3389/fonc.2020.572097

Ejemplares similares

2-Nitroimidazole-Furanoside Derivatives for Hypoxia Imaging—Investigation of Nucleoside Transporter Interaction, (18)F-Labeling and Preclinical PET Imaging
por: Maier, Florian C., et al.
Publicado: (2019)

Synthesis and Evaluation of (99m)Tc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging
por: Ruan, Qing, et al.
Publicado: (2023)

Preparation and Bioevaluation of Novel (99m)Tc-Labeled Complexes with a 2-Nitroimidazole HYNIC Derivative for Imaging Tumor Hypoxia
por: Ruan, Qing, et al.
Publicado: (2021)

Synthesis of a 2-nitroimidazole derivative N-(4-[(18)F]fluorobenzyl)-2-(2-nitro-1H-imidazol-1-yl)-acetamide ([(18) F]FBNA) as PET radiotracer for imaging tumor hypoxia
por: Nario, Arian Pérez, et al.
Publicado: (2022)

Design and Synthesis of Vandetanib Derivatives Containing Nitroimidazole Groups as Tyrosine Kinase Inhibitors in Normoxia and Hypoxia
por: Wei, Huiqiang, et al.
Publicado: (2016)

Convergent synthesis and evaluation of (18)F-labeled azulenic COX2 probes for cancer imaging
por: Nolting, Donald D., et al.
Publicado: (2013)

Recent Advances of (68)Ga-Labeled PET Radiotracers with Nitroimidazole in the Diagnosis of Hypoxia Tumors
por: Nguyen, Anh Thu, et al.
Publicado: (2023)

Synthesis and Biological Activity of Peptide Derivatives of Iodoquinazolinones/Nitroimidazoles
por: Dahiya, Rajiv, et al.
Publicado: (2008)

Synthesis and Biological Evaluation of a New Nitroimidazole-(99m)Tc-Complex for Imaging of Hypoxia in Mice Model
por: Zhang, Qing, et al.
Publicado: (2016)

FAPI-04 PET/CT Using [(18)F]AlF Labeling Strategy: Automatic Synthesis, Quality Control, and In Vivo Assessment in Patient
por: Jiang, Xiao, et al.
Publicado: (2021)

Automatic Production and Preliminary PET Imaging of a New Imaging Agent [(18)F]AlF-FAPT
por: Huang, JiaWen, et al.
Publicado: (2022)

Synthesis of New Branched 2-Nitroimidazole as a Hypoxia Sensitive Linker for Ligand-Targeted Drugs of Paclitaxel
por: Zhang, Qiumeng, et al.
Publicado: (2018)

Biological reduction of nitroimidazole-functionalized gold nanorods for photoacoustic imaging of tumor hypoxia
por: Umehara, Yui, et al.
Publicado: (2019)

Design, Synthesis and Anticancer Evaluation of Nitroimidazole Radiosensitisers
por: Liew, Lydia P., et al.
Publicado: (2023)

Efficient preparation of 2-nitroimidazole nucleosides as precursors for hypoxia PET tracers
por: Križková, Petra, et al.
Publicado: (2016)

Cellular mechanism of action of 2-nitroimidazoles as hypoxia-selective therapeutic agents
por: Rashed, Faisal Bin, et al.
Publicado: (2022)

(18)F-labeled FGFR1 peptide: a new PET probe for subtype FGFR1 receptor imaging
por: Chen, Yang, et al.
Publicado: (2023)

(68)Ga‐nitroimidazole PET/CT imaging of hypoxia in tuberculosis: A case series
por: Bresser, Philippa L, et al.
Publicado: (2022)

Imaging of Tumor Hypoxia With Radionuclide-Labeled Tracers for PET
por: Huang, Yuan, et al.
Publicado: (2021)

Synthesis of New Active Sulfones in the 5-Nitroimidazole Series
por: Benakli, Kamel, et al.
Publicado: (2002)

A phase I study of the nitroimidazole hypoxia marker SR4554 using (19)F magnetic resonance spectroscopy
por: Lee, C P, et al.
Publicado: (2009)

A Prospective Investigation of Tumor Hypoxia Imaging with (68)Ga-Nitroimidazole PET/CT in Patients with Carcinoma of the Cervix Uteri and Comparison with (18)F-FDG PET/CT: Correlation with Immunohistochemistry
por: Mokoala, Kgomotso M. G., et al.
Publicado: (2022)

Imaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-Nitroimidazole-Based Agent “Pimonidazole” in Hypoxia
por: Masaki, Yukiko, et al.
Publicado: (2016)

One-Step (18)F-Labeling of Estradiol Derivative for PET Imaging of Breast Cancer
por: Huang, Hongbo, et al.
Publicado: (2018)

Chemosensitization by lipophilic nitroimidazoles.
por: Twentyman, P. R., et al.
Publicado: (1983)

Electron Ionization of Imidazole and Its Derivative 2-Nitroimidazole
por: Meißner, Rebecca, et al.
Publicado: (2019)

Quick Automatic Synthesis of Solvent-Free 16α-[(18)F] Fluoroestradiol: Comparison of Kryptofix 222 and Tetrabutylammonium Bicarbonate
por: Jiang, Xiao, et al.
Publicado: (2020)

A prospective clinical trial of tumor hypoxia imaging with (18)F-fluoromisonidazole positron emission tomography and computed tomography (F-MISO PET/CT) before and during radiation therapy
por: Tachibana, Izumi, et al.
Publicado: (2013)

Synthesis and Evaluation of [(18)F]FEtLos and [(18)F]AMBF(3)Los as Novel (18)F-Labelled Losartan Derivatives for Molecular Imaging of Angiotensin II Type 1 Receptors
por: Sahylí Ortega Pijeira, Martha, et al.
Publicado: (2020)

Imaging latent tuberculosis infection with radiolabeled nitroimidazoles
por: Ankrah, Alfred O., et al.
Publicado: (2016)

Nitroimidazole derivative-induced fixed drug eruptions: Not so uncommon
por: Sengupta, Parama, et al.
Publicado: (2011)

Radiation Damage Mechanisms of Chemotherapeutically Active Nitroimidazole Derived Compounds
por: Chiarinelli, Jacopo, et al.
Publicado: (2019)

The Role of Nitroreductases in Resistance to Nitroimidazoles
por: Thomas, Carol, et al.
Publicado: (2021)

Recent Advances in (18)F-Labeled Amino Acids Synthesis and Application
por: Wang, Chao, et al.
Publicado: (2022)

Synthesis and in vivo characterization of (18)F-labeled difluoroboron-curcumin derivative for β-amyloid plaque imaging
por: Kim, Hyunjung, et al.
Publicado: (2019)

Design, Synthesis, and Biological Evaluation of a Novel [(18)F]-Labeled Arginine Derivative for Tumor Imaging
por: Huang, Yong, et al.
Publicado: (2023)

Nitroimidazole adducts as markers for tissue hypoxia: mechanistic studies in aerobic normal tissues and tumour cells.
por: Parliament, M. B., et al.
Publicado: (1992)

Analysis of the intra- and intertumoral heterogeneity of hypoxia in pancreatic cancer patients receiving the nitroimidazole tracer pimonidazole
por: Dhani, N C, et al.
Publicado: (2015)

Influence of 2-Nitroimidazoles in the Response of FaDu Cells to Ionizing Radiation and Hypoxia/Reoxygenation Stress
por: Rashed, Faisal Bin, et al.
Publicado: (2023)

(18)F-FDG PET/CT radiomics signature and clinical parameters predict progression-free survival in breast cancer patients: A preliminary study
por: Xu, Xiaojun, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9p7su6r82csbko25a7kuls9889