HOX genes promote cell proliferation and are potential therapeutic targets in adrenocortical tumours

BACKGROUND: Understanding the pathways that drive adrenocortical carcinoma (ACC) is essential to the development of more effective therapies. This study investigates the role of the transcription factor HOXB9 and other HOX factors in ACC and its treatment. METHODS: We used transgenic mouse models to...

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Detalles Bibliográficos
Autores principales: Francis, Jeffrey C., Gardiner, Jennifer R., Renaud, Yoan, Chauhan, Ritika, Weinstein, Yacob, Gomez-Sanchez, Celso, Lefrançois-Martinez, Anne-Marie, Bertherat, Jérôme, Val, Pierre, Swain, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884796/
https://www.ncbi.nlm.nih.gov/pubmed/33214683
http://dx.doi.org/10.1038/s41416-020-01166-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884796/
https://www.ncbi.nlm.nih.gov/pubmed/33214683
http://dx.doi.org/10.1038/s41416-020-01166-z

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