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HOX genes promote cell proliferation and are potential therapeutic targets in adrenocortical tumours
BACKGROUND: Understanding the pathways that drive adrenocortical carcinoma (ACC) is essential to the development of more effective therapies. This study investigates the role of the transcription factor HOXB9 and other HOX factors in ACC and its treatment. METHODS: We used transgenic mouse models to...
Autores principales: | Francis, Jeffrey C., Gardiner, Jennifer R., Renaud, Yoan, Chauhan, Ritika, Weinstein, Yacob, Gomez-Sanchez, Celso, Lefrançois-Martinez, Anne-Marie, Bertherat, Jérôme, Val, Pierre, Swain, Amanda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884796/ https://www.ncbi.nlm.nih.gov/pubmed/33214683 http://dx.doi.org/10.1038/s41416-020-01166-z |
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