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Machine learning modelling of blood lipid biomarkers in familial hypercholesterolaemia versus polygenic/environmental dyslipidaemia

Familial hypercholesterolaemia increases circulating LDL-C levels and leads to premature cardiovascular disease when undiagnosed or untreated. Current guidelines support genetic testing in patients complying with clinical diagnostic criteria and cascade screening of their family members. However, mo...

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Detalles Bibliográficos
Autores principales:	Correia, Marta, Kagenaar, Eva, van Schalkwijk, Daniël Bernardus, Bourbon, Mafalda, Gama-Carvalho, Margarida
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884847/ https://www.ncbi.nlm.nih.gov/pubmed/33589716 http://dx.doi.org/10.1038/s41598-021-83392-w

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