Cargando…

Doxycycline in Extremely Low Dose Improves Glycemic Control and Islet Morphology in Mice Fed a High-Fat Diet

PURPOSE: Chronic low-grade inflammation is detected in obese and diabetic individuals. Tetracyclines, used as antibiotics for years, have been demonstrated to have diverse non-bactericidal effects, including anti-tumor and anti-inflammatory activities. This study aimed to investigate whether doxycyc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yixin, Chen, Yu, Wang, Na, Gu, Shanhong, Wang, Meilin, Fu, Yucai, Wei, Chiju, Xu, Wencan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884939/ https://www.ncbi.nlm.nih.gov/pubmed/33603428 http://dx.doi.org/10.2147/DMSO.S292264

Ejemplares similares

Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in db/db mice
por: Wang, Na, et al.
Publicado: (2017)

Doxycycline Prevents Preclinical Atherosclerosis, Pancreatic Islet Loss and Improves Insulin Secretion after Glycemic Stimulation: Preclinical Study in Individuals with a High-Fat Diet
por: Rodriguez-Hernandez, Alejandrina, et al.
Publicado: (2023)

Augmented reduction of islet β‐cell mass in Goto‐Kakizaki rats fed high‐fat diet and its suppression by pitavastatin treatment
por: Mizukami, Hiroki, et al.
Publicado: (2012)

The Efficacy and Safety of Acellular Matrix Therapy for Diabetic Foot Ulcers: A Meta-Analysis of Randomized Clinical Trials
por: Huang, Wentao, et al.
Publicado: (2020)

Obesity and Overweight Are Independently Associated with Greater Survival in Critically Ill Diabetic Patients: A Retrospective Cohort Study
por: Huang, Wentao, et al.
Publicado: (2021)

Antioxidant effects of fucoxanthin rich powder in rats fed with high fat diet
por: Ha, Ae Wha, et al.
Publicado: (2013)

Altered pancreatic islet morphology and function in SGLT1 knockout mice on a glucose-deficient, fat-enriched diet
por: Mühlemann, Markus, et al.
Publicado: (2018)

Chronopharmacology of simvastatin on hyperlipidaemia in high‐fat diet‐fed obese mice
por: Li, Huan, et al.
Publicado: (2020)

A novel mice model of metabolic syndrome: the high-fat-high-fructose diet-fed ICR mice
por: Zhuhua, Zhang, et al.
Publicado: (2015)

Resistant dextrin reduces obesity and attenuates adipose tissue inflammation in high-fat diet-fed mice
por: Hu, Qiuyue, et al.
Publicado: (2020)

Prevotella copri increases fat accumulation in pigs fed with formula diets
por: Chen, Congying, et al.
Publicado: (2021)

Augmented Insulin and Leptin Resistance of High Fat Diet-Fed APPswe/PS1dE9 Transgenic Mice Exacerbate Obesity and Glycemic Dysregulation
por: Lee, Yi-Heng, et al.
Publicado: (2018)

CSAD Ameliorates Lipid Accumulation in High-Fat Diet-Fed Mice
por: Tan, Rongrong, et al.
Publicado: (2022)

Polydextrose Alleviates Adipose Tissue Inflammation and Modulates the Gut Microbiota in High-Fat Diet-Fed Mice
por: Hu, Qiuyue, et al.
Publicado: (2022)

An Amino Acids Mixture Attenuates Glycemic Impairment but not Affects Adiposity Development in Rats Fed with AGEs-containing Diet
por: Liao, Yi-Hung, et al.
Publicado: (2018)

The Effect of Inflammation on the Formation of Thyroid Nodules
por: Li, Zexin, et al.
Publicado: (2020)

Hepatic Nampt Deficiency Aggravates Dyslipidemia and Fatty Liver in High Fat Diet Fed Mice
por: Wang, Dao-Xin, et al.
Publicado: (2023)

In Vivo Lipid Regulation Mechanism of Polygoni Multiflori Radix in High-Fat Diet Fed Rats
por: Lin, Pei, et al.
Publicado: (2014)

Alteration of Loperamide-Induced Prostate Relaxation in High-Fat Diet-Fed Rats
por: Hsu, Sheng-Lung, et al.
Publicado: (2014)

Tetramethylpyrazine reduces inflammation in the livers of mice fed a high fat diet
por: Chen, Bing, et al.
Publicado: (2019)

Long-term Effect of Islet Transplantation on Glycemic Variability
por: Bertuzzi, Federico, et al.
Publicado: (2018)

Surgical fat removal exacerbates metabolic disorders but not atherogenesis in LDLR(−/−) mice fed on high-fat diet
por: Liu, Lin, et al.
Publicado: (2019)

Effects of Lipid Regulation Using Raw and Processed Radix Polygoni Multiflori in Rats Fed a High-Fat Diet
por: Li, Na, et al.
Publicado: (2012)

Influence of α-lipoic Acid on Morphology of Organs of Rabbits Fed a High Fat Diet with the Addition of Oxidised Rapeseed Oil
por: Stawiarska-Pięta, Barbara, et al.
Publicado: (2017)

Chronic Urotensin-II Administration Improves Whole-Body Glucose Tolerance in High-Fat Diet-Fed Mice
por: Chen, Xi, et al.
Publicado: (2019)

Limonin, an AMPK Activator, Inhibits Hepatic Lipid Accumulation in High Fat Diet Fed Mice
por: Wang, Si-wei, et al.
Publicado: (2022)

PTEN Inhibition Improves Muscle Regeneration in Mice Fed a High-Fat Diet
por: Hu, Zhaoyong, et al.
Publicado: (2010)

Transcriptomic Analysis of High Fat Diet Fed Mouse Brain Cortex
por: Yoon, Gwangho, et al.
Publicado: (2019)

Spleen proteomics data from high fat diet fed mice
por: Svahn, Sara L, et al.
Publicado: (2020)

Ion channels alterations in the forebrain of high-fat diet fed rats
por: Roy, Proshanta, et al.
Publicado: (2021)

Nuciferine modulates the gut microbiota and prevents obesity in high-fat diet-fed rats
por: Wang, Yu, et al.
Publicado: (2020)

Piperine potentiates the hypocholesterolemic effect of curcumin in rats fed on a high fat diet
por: TU, YAOSHENG, et al.
Publicado: (2014)

Effects of swimming before and during pregnancy on placental angiogenesis and perinatal outcome in high-fat diet-fed mice
por: Zhu, Xiaofeng, et al.
Publicado: (2023)

Effects of herbal mixture extracts on obesity in rats fed a high-fat diet
por: Chien, Mei-Yin, et al.
Publicado: (2016)

Chronic administration of Angelica sinensis polysaccharide effectively improves fatty liver and glucose homeostasis in high-fat diet-fed mice
por: Wang, Kaiping, et al.
Publicado: (2016)

Anti-obesity effects of Rapha diet® preparation in mice fed a high-fat diet
por: Kim, Jihyun, et al.
Publicado: (2012)

Protective Effects of Restricted Diet and Antioxidants on Testis Tissue in Rats Fed with High-Fat Diet
por: Mohammadi Roushandeh, Amaneh, et al.
Publicado: (2015)

Regressive Effect of Myricetin on Hepatic Steatosis in Mice Fed a High-Fat Diet
por: Xia, Shu-Fang, et al.
Publicado: (2016)

Gold nanoparticles improve metabolic profile of mice fed a high-fat diet
por: Chen, Hui, et al.
Publicado: (2018)

The effects of Momordica charantia on obesity and lipid profiles of mice fed a high-fat diet
por: Wang, Jun, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ic0scd0guvd3d6mesbd2r3vkpv