Cargando…
Intracellular Group A Streptococcus Induces Golgi Fragmentation To Impair Host Defenses through Streptolysin O and NAD-Glycohydrolase
Group A Streptococcus (GAS; Streptococcus pyogenes) is a major human pathogen that causes streptococcal pharyngitis, skin and soft tissue infections, and life-threatening conditions such as streptococcal toxic-shock syndrome. During infection, GAS not only invades diverse host cells but also injects...
Autores principales: | Nozawa, Takashi, Iibushi, Junpei, Toh, Hirotaka, Minowa-Nozawa, Atsuko, Murase, Kazunori, Aikawa, Chihiro, Nakagawa, Ichiro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885101/ https://www.ncbi.nlm.nih.gov/pubmed/33563838 http://dx.doi.org/10.1128/mBio.01974-20 |
Ejemplares similares
-
Group A Streptococcus NAD-Glycohydrolase Inhibits Caveolin 1-Mediated Internalization Into Human Epithelial Cells
por: Toh, Hirotaka, et al.
Publicado: (2019) -
Autophagy Receptor Tollip Facilitates Bacterial Autophagy by Recruiting Galectin-7 in Response to Group A Streptococcus Infection
por: Lin, Ching-Yu, et al.
Publicado: (2020) -
Rab41-mediated ESCRT machinery repairs membrane rupture by a bacterial toxin in xenophagy
por: Nozawa, Takashi, et al.
Publicado: (2023) -
Bcl-xL Affects Group A Streptococcus-Induced Autophagy Directly, by Inhibiting Fusion between Autophagosomes and Lysosomes, and Indirectly, by Inhibiting Bacterial Internalization via Interaction with Beclin 1-UVRAG
por: Nakajima, Shintaro, et al.
Publicado: (2017) -
TBC1D9 regulates TBK1 activation through Ca(2+) signaling in selective autophagy
por: Nozawa, Takashi, et al.
Publicado: (2020)