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Topoisomerase 2β Induces DNA Breaks To Regulate Human Papillomavirus Replication
Topoisomerases regulate higher-order chromatin structures through the transient breaking and religating of one or both strands of the phosphodiester backbone of duplex DNA. TOP2β is a type II topoisomerase that induces double-strand DNA breaks at topologically associated domains (TADS) to relieve to...
Autores principales: | Kaminski, Paul, Hong, Shiyuan, Kono, Takeyuki, Hoover, Paul, Laimins, Laimonis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885102/ https://www.ncbi.nlm.nih.gov/pubmed/33563836 http://dx.doi.org/10.1128/mBio.00005-21 |
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