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Resistance to a Nucleoside Analog Antiviral Drug from More Rapid Extension of Drug-Containing Primers
Nucleoside analogs are mainstays of antiviral therapy. Although resistance to these drugs hinders their use, understanding resistance can illuminate mechanisms of the drugs and their targets. Certain nucleoside analogs, such as ganciclovir (GCV), a leading therapy for human cytomegalovirus (HCMV), c...
Autores principales: | Chen, Han, Lawler, Jessica L., Filman, David J., Hogle, James M., Coen, Donald M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885103/ https://www.ncbi.nlm.nih.gov/pubmed/33563814 http://dx.doi.org/10.1128/mBio.03492-20 |
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