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ApmA Is a Unique Aminoglycoside Antibiotic Acetyltransferase That Inactivates Apramycin

Apramycin is an aminoglycoside antibiotic with the potential to be developed to combat multidrug-resistant pathogens. Its unique structure evades the clinically widespread mechanisms of aminoglycoside resistance that currently compromise the efficacy of other members in this drug class. Of the amino...

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Detalles Bibliográficos
Autores principales:	Bordeleau, Emily, Stogios, Peter J., Evdokimova, Elena, Koteva, Kalinka, Savchenko, Alexei, Wright, Gerard D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885111/ https://www.ncbi.nlm.nih.gov/pubmed/33563840 http://dx.doi.org/10.1128/mBio.02705-20

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