Nrf2 Regulates Granuloma Formation and Macrophage Activation during Mycobacterium avium Infection via Mediating Nramp1 and HO-1 Expressions

Nrf2 is a redox-sensitive transcription factor that is thought to be important in protection against intracellular pathogens. To determine the protective role of Nrf2 in the host defense against Mycobacterium avium complex (MAC), both wild-type and Nrf2-deficient mice were intranasally infected with...

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Detalles Bibliográficos
Autores principales: Nakajima, Masayuki, Matsuyama, Masashi, Kawaguchi, Mio, Kiwamoto, Takumi, Matsuno, Yosuke, Morishima, Yuko, Yoshida, Kazufumi, Sherpa, Mingma, Yazaki, Kai, Osawa, Hajime, Muratani, Masafumi, Ishii, Yukio, Hizawa, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885113/
https://www.ncbi.nlm.nih.gov/pubmed/33563837
http://dx.doi.org/10.1128/mBio.01947-20

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