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Rhabdomyolysis Secondary to Hypothyroidism: Report of a Case

Rhabdomyolysis has many causes; however, hypothyroidism is a rare cause of such a condition. Usually, management is similar in many cases, but some exceptions do exist, especially in the case of hypothyroidism. Thus, we reviewed the literature to investigate further precipitant factors, clinical pre...

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Autores principales: Alshamam, Mohsen S, Gurung, Dawa O, Nso, Nso, Saliaj, Merjona, Seitaj, Adja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885184/
https://www.ncbi.nlm.nih.gov/pubmed/33643723
http://dx.doi.org/10.7759/cureus.12746
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author Alshamam, Mohsen S
Gurung, Dawa O
Nso, Nso
Saliaj, Merjona
Seitaj, Adja
author_facet Alshamam, Mohsen S
Gurung, Dawa O
Nso, Nso
Saliaj, Merjona
Seitaj, Adja
author_sort Alshamam, Mohsen S
collection PubMed
description Rhabdomyolysis has many causes; however, hypothyroidism is a rare cause of such a condition. Usually, management is similar in many cases, but some exceptions do exist, especially in the case of hypothyroidism. Thus, we reviewed the literature to investigate further precipitant factors, clinical presentations, complications, management, and prognoses. We report a 19-year-old male with a history of hypothyroidism who was brought in for questionable suicidal ideation. Although asymptomatic, he was found to have an acute kidney injury (AKI). Further investigations revealed significantly elevated levels of creatine kinase (CK) and thyroid-stimulating hormone (TSH) in the setting of medication non-compliance. Management with intravenous (IV) fluids and thyroid hormone replacement resulted in an improvement in AKI and CK levels.
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spelling pubmed-78851842021-02-27 Rhabdomyolysis Secondary to Hypothyroidism: Report of a Case Alshamam, Mohsen S Gurung, Dawa O Nso, Nso Saliaj, Merjona Seitaj, Adja Cureus Endocrinology/Diabetes/Metabolism Rhabdomyolysis has many causes; however, hypothyroidism is a rare cause of such a condition. Usually, management is similar in many cases, but some exceptions do exist, especially in the case of hypothyroidism. Thus, we reviewed the literature to investigate further precipitant factors, clinical presentations, complications, management, and prognoses. We report a 19-year-old male with a history of hypothyroidism who was brought in for questionable suicidal ideation. Although asymptomatic, he was found to have an acute kidney injury (AKI). Further investigations revealed significantly elevated levels of creatine kinase (CK) and thyroid-stimulating hormone (TSH) in the setting of medication non-compliance. Management with intravenous (IV) fluids and thyroid hormone replacement resulted in an improvement in AKI and CK levels. Cureus 2021-01-17 /pmc/articles/PMC7885184/ /pubmed/33643723 http://dx.doi.org/10.7759/cureus.12746 Text en Copyright © 2021, Alshamam et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Alshamam, Mohsen S
Gurung, Dawa O
Nso, Nso
Saliaj, Merjona
Seitaj, Adja
Rhabdomyolysis Secondary to Hypothyroidism: Report of a Case
title Rhabdomyolysis Secondary to Hypothyroidism: Report of a Case
title_full Rhabdomyolysis Secondary to Hypothyroidism: Report of a Case
title_fullStr Rhabdomyolysis Secondary to Hypothyroidism: Report of a Case
title_full_unstemmed Rhabdomyolysis Secondary to Hypothyroidism: Report of a Case
title_short Rhabdomyolysis Secondary to Hypothyroidism: Report of a Case
title_sort rhabdomyolysis secondary to hypothyroidism: report of a case
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885184/
https://www.ncbi.nlm.nih.gov/pubmed/33643723
http://dx.doi.org/10.7759/cureus.12746
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