Cargando…

Genome-wide analysis identifies critical DNA methylations within NTRKs genes in colorectal cancer

BACKGROUND: Neurotrophic tropomyosin receptor kinases (NTRKs) are a gene family function as oncogene or tumor suppressor gene in distinct cancers. We aimed to investigate the methylation and expression profiles and prognostic value of NTRKs gene in colorectal cancer (CRC). METHODS: An analysis of DN...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Zijian, Huang, Zenghong, Luo, Yanxin, Zou, Qi, Bai, Liangliang, Tang, Guannan, Wang, Xiaolin, Cao, Guangwen, Huang, Meijin, Xiang, Jun, Yu, Huichuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885252/ https://www.ncbi.nlm.nih.gov/pubmed/33593392 http://dx.doi.org/10.1186/s12967-021-02740-6

Ejemplares similares

Nomograms for Prediction of Molecular Phenotypes in Colorectal Cancer
por: Yu, Zhuojun, et al.
Publicado: (2020)

Improved Survival Outcome and Access to Cancer Screening from Hemorrhoid in Patients with Rectal Cancer
por: Zou, Qi, et al.
Publicado: (2020)

Revisiting NTRKs as an emerging oncogene in hematological malignancies
por: Joshi, Sunil K., et al.
Publicado: (2019)

The Effects of Sleeve Gastrectomy on Glucose Metabolism and Glucagon-Like Peptide 1 in Goto-Kakizaki Rats
por: Li, Laiyuan, et al.
Publicado: (2018)

Aberrant methylation in neurofunctional gene serves as a hallmark of tumorigenesis and progression in colorectal cancer
por: Li, Xuan, et al.
Publicado: (2023)

Time to lowest postoperative carcinoembryonic antigen level is predictive on survival outcome in rectal cancer
por: Yu, Huichuan, et al.
Publicado: (2016)

DNA methylation-based signature of CD8+ tumor-infiltrating lymphocytes enables evaluation of immune response and prognosis in colorectal cancer
por: Zou, Qi, et al.
Publicado: (2021)

RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A‐YTHDF2‐dependent manner
por: Shen, Dingcheng, et al.
Publicado: (2023)

Silence of a dependence receptor CSF1R in colorectal cancer cells activates tumor-associated macrophages
por: Zhu, Mingxuan, et al.
Publicado: (2022)

Fasting-mimicking diet synergizes with ferroptosis against quiescent, chemotherapy-resistant cells
por: Liu, Xiaoxia, et al.
Publicado: (2023)

Clinical spectrum of rectal cancer identifies hallmarks of early‐onset patients and next‐generation treatment strategies
por: Shen, Dingcheng, et al.
Publicado: (2022)

Clinical atlas of rectal cancer highlights the barriers and insufficient interventions underlying the unfavorable outcomes in older patients
por: Zhao, Zhuoyang, et al.
Publicado: (2023)

Prognostic value of carcinoembryonic antigen level in patients with colorectal cancer liver metastasis treated with percutaneous microwave ablation under ultrasound guidance
por: Peng, Shaoyong, et al.
Publicado: (2018)

Anti-Tumor Activity of AZD4547 Against NTRK1 Fusion Positive Cancer Cells Through Inhibition of NTRKs
por: Cho, Hanna, et al.
Publicado: (2021)

Radiological lymph‐node size improves the prognostic value of systemic inflammation index in rectal cancer with pathologically negative nodes
por: Peng, Shaoyong, et al.
Publicado: (2023)

Current treatment and surveillance modalities are not sufficient for advanced stage III colon cancer: Result from a multicenter cohort analysis
por: Li, Juan, et al.
Publicado: (2021)

Radiomic signature of the FOWARC trial predicts pathological response to neoadjuvant treatment in rectal cancer
por: Zhuang, Zhuokai, et al.
Publicado: (2021)

Metabolomics reveals that CAF-derived lipids promote colorectal cancer peritoneal metastasis by enhancing membrane fluidity
por: Peng, Shaoyong, et al.
Publicado: (2022)

Screening and identifying of biomarkers in early colorectal cancer and adenoma based on genome-wide methylation profiles
por: He, Chungang, et al.
Publicado: (2023)

Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer
por: McInnes, Tyler, et al.
Publicado: (2017)

Genome-wide methylation profiling of early colorectal cancer using an Illumina Infinium Methylation EPIC BeadChip
por: Wu, Yu-Ling, et al.
Publicado: (2022)

Genomic G-quadruplex folding triggers a cytokine-mediated inflammatory feedback loop to aggravate inflammatory diseases
por: Wang, Xiaolin, et al.
Publicado: (2022)

Levels of human replication factor C4, a clamp loader, correlate with tumor progression and predict the prognosis for colorectal cancer
por: Xiang, Jun, et al.
Publicado: (2014)

Screening Physical Solvents for Methyl Mercaptan Absorption Using Quantum Chemical Calculation Coupled with Experiments
por: Liang, Pengju, et al.
Publicado: (2023)

Investigation of a new graphene strain sensor based on surface plasmon resonance
por: Ma, Zenghong, et al.
Publicado: (2020)

A genome-wide DNA methylation study in colorectal carcinoma
por: Kibriya, Muhammad G, et al.
Publicado: (2011)

Landscape of Genome-Wide DNA Methylation of Colorectal Cancer Metastasis
por: Ili, Carmen, et al.
Publicado: (2020)

Clinical outcomes of active specific immunotherapy in advanced colorectal cancer and suspected minimal residual colorectal cancer: a meta-analysis and system review
por: Rao, Benqiang, et al.
Publicado: (2011)

Genome-wide methylation profiling identified novel differentially hypermethylated biomarker MPPED2 in colorectal cancer
por: Gu, Simeng, et al.
Publicado: (2019)

The Effect of Correction Algorithms on Knee Kinematics and Kinetics during Gait of Patients with Knee Osteoarthritis
por: Ulbricht, Hanna, et al.
Publicado: (2020)

Overexpression of MEKK2 is associated with colorectal carcinogenesis
por: JIANG, LI, et al.
Publicado: (2013)

Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules
por: Kelly, Theresa K., et al.
Publicado: (2012)

Estimating genome-wide DNA methylation heterogeneity with methylation patterns
por: Lin, Pei-Yu, et al.
Publicado: (2023)

Data in support of genome-wide identification of lineage-specific genes within Caenorhabditis elegans
por: Zhou, Kun, et al.
Publicado: (2015)

Proteome-wide identification of arginine methylation in colorectal cancer tissues from patients
por: Lim, Yongchul, et al.
Publicado: (2020)

Molecular Typing and Clinical Characteristics of Synchronous Multiple Primary Colorectal Cancer
por: Zhao, Yandong, et al.
Publicado: (2022)

Risk of eighteen genome-wide association study-identified genetic variants for colorectal cancer and colorectal adenoma in Han Chinese
por: Tan, Chunwen, et al.
Publicado: (2016)

Neoadjuvant chemoradiotherapy versus neoadjuvant chemotherapy alone for patients with locally advanced rectal cancer: a propensity-score-matched analysis combined with SEER validation
por: Wu, Jingjing, et al.
Publicado: (2023)

Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood
por: Huang, R C, et al.
Publicado: (2015)

Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers
por: Decock, Anneleen, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_7uui0t51ruq06pq370fkf8j7en