Comparative validation of the BOADICEA and Tyrer-Cuzick breast cancer risk models incorporating classical risk factors and polygenic risk in a population-based prospective cohort of women of European ancestry

BACKGROUND: The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) and the Tyrer-Cuzick breast cancer risk prediction models are commonly used in clinical practice and have recently been extended to include polygenic risk scores (PRS). In addition, BOADICEA...

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Detalles Bibliográficos
Autores principales: Pal Choudhury, Parichoy, Brook, Mark N., Hurson, Amber N., Lee, Andrew, Mulder, Charlotta V., Coulson, Penny, Schoemaker, Minouk J., Jones, Michael E., Swerdlow, Anthony J., Chatterjee, Nilanjan, Antoniou, Antonis C., Garcia-Closas, Montserrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885342/
https://www.ncbi.nlm.nih.gov/pubmed/33588869
http://dx.doi.org/10.1186/s13058-021-01399-7

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