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The role of pro-opiomelanocortin in the ACTH–cortisol dissociation of sepsis

BACKGROUND: Sepsis is typically hallmarked by high plasma (free) cortisol and suppressed cortisol breakdown, while plasma adrenocorticotropic hormone (ACTH) is not increased, referred to as ‘ACTH–cortisol dissociation.’ We hypothesized that sepsis acutely activates the hypothalamus to generate, via...

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Detalles Bibliográficos
Autores principales:	Téblick, Arno, Vander Perre, Sarah, Pauwels, Lies, Derde, Sarah, Van Oudenhove, Tim, Langouche, Lies, Van den Berghe, Greet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885358/ https://www.ncbi.nlm.nih.gov/pubmed/33593393 http://dx.doi.org/10.1186/s13054-021-03475-y

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