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GABAergic neuron-specific whole-brain transduction by AAV-PHP.B incorporated with a new GAD65 promoter

GABAergic interneurons play a critical role in tuning neural networks in the central nervous system, and their defects are associated with neuropsychiatric disorders. Currently, the mDlx enhancer is solely used for adeno-associated virus (AAV) vector-mediated transgene delivery into cortical interne...

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Detalles Bibliográficos
Autores principales:	Hoshino, Chiaki, Konno, Ayumu, Hosoi, Nobutake, Kaneko, Ryosuke, Mukai, Ryo, Nakai, Junichi, Hirai, Hirokazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885384/ https://www.ncbi.nlm.nih.gov/pubmed/33588899 http://dx.doi.org/10.1186/s13041-021-00746-1

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