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Characterizing RNA stability genome-wide through combined analysis of PRO-seq and RNA-seq data
BACKGROUND: The concentrations of distinct types of RNA in cells result from a dynamic equilibrium between RNA synthesis and decay. Despite the critical importance of RNA decay rates, current approaches for measuring them are generally labor-intensive, limited in sensitivity, and/or disruptive to no...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885420/ https://www.ncbi.nlm.nih.gov/pubmed/33588838 http://dx.doi.org/10.1186/s12915-021-00949-x |