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Characterizing RNA stability genome-wide through combined analysis of PRO-seq and RNA-seq data

BACKGROUND: The concentrations of distinct types of RNA in cells result from a dynamic equilibrium between RNA synthesis and decay. Despite the critical importance of RNA decay rates, current approaches for measuring them are generally labor-intensive, limited in sensitivity, and/or disruptive to no...

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Detalles Bibliográficos
Autores principales:	Blumberg, Amit, Zhao, Yixin, Huang, Yi-Fei, Dukler, Noah, Rice, Edward J., Chivu, Alexandra G., Krumholz, Katie, Danko, Charles G., Siepel, Adam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885420/ https://www.ncbi.nlm.nih.gov/pubmed/33588838 http://dx.doi.org/10.1186/s12915-021-00949-x

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