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A specific tRNA half, 5’tiRNA-His-GTG, responds to hypoxia via the HIF1α/ANG axis and promotes colorectal cancer progression by regulating LATS2

BACKGROUND: Currently, tRNA-derived small RNAs (tsRNAs) are recognized as a novel and potential type of non-coding RNAs (ncRNAs), which participate in various cellular processes and play an essential role in cancer progression. However, tsRNAs involvement in colorectal cancer (CRC) progression remai...

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Detalles Bibliográficos
Autores principales: Tao, En-Wei, Wang, Hao-Lian, Cheng, Wing Yin, Liu, Qian-Qian, Chen, Ying-Xuan, Gao, Qin-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885485/
https://www.ncbi.nlm.nih.gov/pubmed/33588913
http://dx.doi.org/10.1186/s13046-021-01836-7