Low Cycle Threshold Value in Xpert MTB/RIF Assay May Herald False Detection of Tuberculosis and Rifampicin Resistance: A Study of Two Cases

We report 2 cases for whom Xpert MTB/RIF falsely signaled rifampicin-resistant tuberculosis, based on unusually low cycle threshold and 3 of 5 probes missing. Other mycobacterial tests were negative. Further optimization of the Xpert MTB/RIF algorithm is warranted.

Detalles Bibliográficos
Autores principales: Ngabonziza, Jean Claude S, Decroo, Tom, Maniliho, Rodrigue, Habimana, Yves M, Van Deun, Armand, de Jong, Bouke C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885858/
https://www.ncbi.nlm.nih.gov/pubmed/33614819
http://dx.doi.org/10.1093/ofid/ofab034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885858/
https://www.ncbi.nlm.nih.gov/pubmed/33614819
http://dx.doi.org/10.1093/ofid/ofab034

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