Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids

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Nucleocapsid (N) protein of the SARS-CoV-2 virus packages the viral genome into well-defined ribonucleoprotein particles, but the molecular pathway is still unclear. N-protein is dimeric and consists of two folded domains with nucleic acid (NA) binding sites, surrounded by intrinsically disordered r...

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Detalles Bibliográficos
Autores principales: Zhao, Huaying, Wu, Di, Nguyen, Ai, Li, Yan, Adão, Regina C., Valkov, Eugene, Patterson, George H., Piszczek, Grzegorz, Schuck, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885910/
https://www.ncbi.nlm.nih.gov/pubmed/33594360
http://dx.doi.org/10.1101/2021.02.08.430344

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