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Early introductions and community transmission of SARS-CoV-2 variant B.1.1.7 in the United States
The emergence and spread of SARS-CoV-2 lineage B.1.1.7, first detected in the United Kingdom, has become a global public health concern because of its increased transmissibility. Over 2500 COVID-19 cases associated with this variant have been detected in the US since December 2020, but the extent of...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885932/ https://www.ncbi.nlm.nih.gov/pubmed/33594373 http://dx.doi.org/10.1101/2021.02.10.21251540 |
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| author | Alpert, Tara Brito, Anderson F. Lasek-Nesselquist, Erica Rothman, Jessica Valesano, Andrew L. MacKay, Matthew J. Petrone, Mary E. Breban, Mallery I. Watkins, Anne E. Vogels, Chantal B.F. Kalinich, Chaney C. Dellicour, Simon Russell, Alexis Kelly, John P. Shudt, Matthew Plitnick, Jonathan Schneider, Erasmus Fitzsimmons, William J. Khullar, Gaurav Metti, Jessica Dudley, Joel T. Nash, Megan Beaubier, Nike Wang, Jianhui Liu, Chen Hui, Pei Muyombwe, Anthony Downing, Randy Razeq, Jafar Bart, Stephen M. Grills, Ardath Morrison, Stephanie M. Murphy, Steven Neal, Caleb Laszlo, Eva Rennert, Hanna Cushing, Melissa Westblade, Lars Velu, Priya Craney, Arryn Fauntleroy, Kathy A. Peaper, David R. Landry, Marie L. Cook, Peter W. Fauver, Joseph R. Mason, Christopher E. Lauring, Adam S. George, Kirsten St. MacCannell, Duncan R. Grubaugh, Nathan D. |
| author_facet | Alpert, Tara Brito, Anderson F. Lasek-Nesselquist, Erica Rothman, Jessica Valesano, Andrew L. MacKay, Matthew J. Petrone, Mary E. Breban, Mallery I. Watkins, Anne E. Vogels, Chantal B.F. Kalinich, Chaney C. Dellicour, Simon Russell, Alexis Kelly, John P. Shudt, Matthew Plitnick, Jonathan Schneider, Erasmus Fitzsimmons, William J. Khullar, Gaurav Metti, Jessica Dudley, Joel T. Nash, Megan Beaubier, Nike Wang, Jianhui Liu, Chen Hui, Pei Muyombwe, Anthony Downing, Randy Razeq, Jafar Bart, Stephen M. Grills, Ardath Morrison, Stephanie M. Murphy, Steven Neal, Caleb Laszlo, Eva Rennert, Hanna Cushing, Melissa Westblade, Lars Velu, Priya Craney, Arryn Fauntleroy, Kathy A. Peaper, David R. Landry, Marie L. Cook, Peter W. Fauver, Joseph R. Mason, Christopher E. Lauring, Adam S. George, Kirsten St. MacCannell, Duncan R. Grubaugh, Nathan D. |
| author_sort | Alpert, Tara |
| collection | PubMed |
| description | The emergence and spread of SARS-CoV-2 lineage B.1.1.7, first detected in the United Kingdom, has become a global public health concern because of its increased transmissibility. Over 2500 COVID-19 cases associated with this variant have been detected in the US since December 2020, but the extent of establishment is relatively unknown. Using travel, genomic, and diagnostic data, we highlight the primary ports of entry for B.1.1.7 in the US and locations of possible underreporting of B.1.1.7 cases. Furthermore, we found evidence for many independent B.1.1.7 establishments starting in early December 2020, followed by interstate spread by the end of the month. Finally, we project that B.1.1.7 will be the dominant lineage in many states by mid to late March. Thus, genomic surveillance for B.1.1.7 and other variants urgently needs to be enhanced to better inform the public health response. |
| format | Online Article Text |
| id | pubmed-7885932 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Cold Spring Harbor Laboratory |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-78859322021-02-17 Early introductions and community transmission of SARS-CoV-2 variant B.1.1.7 in the United States Alpert, Tara Brito, Anderson F. Lasek-Nesselquist, Erica Rothman, Jessica Valesano, Andrew L. MacKay, Matthew J. Petrone, Mary E. Breban, Mallery I. Watkins, Anne E. Vogels, Chantal B.F. Kalinich, Chaney C. Dellicour, Simon Russell, Alexis Kelly, John P. Shudt, Matthew Plitnick, Jonathan Schneider, Erasmus Fitzsimmons, William J. Khullar, Gaurav Metti, Jessica Dudley, Joel T. Nash, Megan Beaubier, Nike Wang, Jianhui Liu, Chen Hui, Pei Muyombwe, Anthony Downing, Randy Razeq, Jafar Bart, Stephen M. Grills, Ardath Morrison, Stephanie M. Murphy, Steven Neal, Caleb Laszlo, Eva Rennert, Hanna Cushing, Melissa Westblade, Lars Velu, Priya Craney, Arryn Fauntleroy, Kathy A. Peaper, David R. Landry, Marie L. Cook, Peter W. Fauver, Joseph R. Mason, Christopher E. Lauring, Adam S. George, Kirsten St. MacCannell, Duncan R. Grubaugh, Nathan D. medRxiv Article The emergence and spread of SARS-CoV-2 lineage B.1.1.7, first detected in the United Kingdom, has become a global public health concern because of its increased transmissibility. Over 2500 COVID-19 cases associated with this variant have been detected in the US since December 2020, but the extent of establishment is relatively unknown. Using travel, genomic, and diagnostic data, we highlight the primary ports of entry for B.1.1.7 in the US and locations of possible underreporting of B.1.1.7 cases. Furthermore, we found evidence for many independent B.1.1.7 establishments starting in early December 2020, followed by interstate spread by the end of the month. Finally, we project that B.1.1.7 will be the dominant lineage in many states by mid to late March. Thus, genomic surveillance for B.1.1.7 and other variants urgently needs to be enhanced to better inform the public health response. Cold Spring Harbor Laboratory 2021-03-11 /pmc/articles/PMC7885932/ /pubmed/33594373 http://dx.doi.org/10.1101/2021.02.10.21251540 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which allows reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator. |
| spellingShingle | Article Alpert, Tara Brito, Anderson F. Lasek-Nesselquist, Erica Rothman, Jessica Valesano, Andrew L. MacKay, Matthew J. Petrone, Mary E. Breban, Mallery I. Watkins, Anne E. Vogels, Chantal B.F. Kalinich, Chaney C. Dellicour, Simon Russell, Alexis Kelly, John P. Shudt, Matthew Plitnick, Jonathan Schneider, Erasmus Fitzsimmons, William J. Khullar, Gaurav Metti, Jessica Dudley, Joel T. Nash, Megan Beaubier, Nike Wang, Jianhui Liu, Chen Hui, Pei Muyombwe, Anthony Downing, Randy Razeq, Jafar Bart, Stephen M. Grills, Ardath Morrison, Stephanie M. Murphy, Steven Neal, Caleb Laszlo, Eva Rennert, Hanna Cushing, Melissa Westblade, Lars Velu, Priya Craney, Arryn Fauntleroy, Kathy A. Peaper, David R. Landry, Marie L. Cook, Peter W. Fauver, Joseph R. Mason, Christopher E. Lauring, Adam S. George, Kirsten St. MacCannell, Duncan R. Grubaugh, Nathan D. Early introductions and community transmission of SARS-CoV-2 variant B.1.1.7 in the United States |
| title | Early introductions and community transmission of SARS-CoV-2 variant B.1.1.7 in the United States |
| title_full | Early introductions and community transmission of SARS-CoV-2 variant B.1.1.7 in the United States |
| title_fullStr | Early introductions and community transmission of SARS-CoV-2 variant B.1.1.7 in the United States |
| title_full_unstemmed | Early introductions and community transmission of SARS-CoV-2 variant B.1.1.7 in the United States |
| title_short | Early introductions and community transmission of SARS-CoV-2 variant B.1.1.7 in the United States |
| title_sort | early introductions and community transmission of sars-cov-2 variant b.1.1.7 in the united states |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885932/ https://www.ncbi.nlm.nih.gov/pubmed/33594373 http://dx.doi.org/10.1101/2021.02.10.21251540 |
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