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A cell-penetrating MARCKS mimetic selectively triggers cytolytic death in glioblastoma

Glioblastoma (GBM) is an aggressive malignancy with limited effectiveness of standard of care therapies including surgery, radiation, and temozolomide chemotherapy necessitating novel therapeutics. Unfortunately, GBMs also harbor several signaling alterations that protect them from traditional thera...

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Detalles Bibliográficos
Autores principales: Eustace, Nicholas J., Anderson, Joshua C., Warram, Jason M., Widden, Hayley N., Pedersen, Rune T., Alrefai, Hasan, Patel, Zeel, Hicks, Patricia H., Placzek, William J., Gillespie, G. Yancey, Hjelmeland, Anita B., Willey, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885995/
https://www.ncbi.nlm.nih.gov/pubmed/33077834
http://dx.doi.org/10.1038/s41388-020-01511-9

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