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Native Chemical Ligation of Highly Hydrophobic Peptides in Ionic Liquid-Containing Media

[Image: see text] The chemical synthesis of a highly hydrophobic membrane-associated peptide by native chemical ligation (NCL) in an ionic liquid (IL) [C(2)mim][OAc]/buffer mixture was achieved by employing peptide concentrations up to 11 mM. NCL was studied at different pH and water content and com...

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Detalles Bibliográficos
Autores principales:	Baumruck, Andreas C., Yang, Jie, Thomas, Gerke-Fabian, Beyer, Luisa I., Tietze, Daniel, Tietze, Alesia A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886022/ https://www.ncbi.nlm.nih.gov/pubmed/33400874 http://dx.doi.org/10.1021/acs.joc.0c02498

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