Cargando…

Recent advances in understanding endocrine disruptors: DDT and related compounds

Endocrine-disrupting compounds (EDCs) are environmental contaminants that modulate estrogen, androgen, and thyroid hormone receptor signaling and it has been hypothesized that human exposures to EDCs induce multiple adverse health effects. Some of these responses include male and female reproductive...

Descripción completa

Detalles Bibliográficos
Autor principal: Safe, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty Opinions Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886056/
https://www.ncbi.nlm.nih.gov/pubmed/33659939
http://dx.doi.org/10.12703/b/9-7
_version_ 1783651716478009344
author Safe, Stephen
author_facet Safe, Stephen
author_sort Safe, Stephen
collection PubMed
description Endocrine-disrupting compounds (EDCs) are environmental contaminants that modulate estrogen, androgen, and thyroid hormone receptor signaling and it has been hypothesized that human exposures to EDCs induce multiple adverse health effects. Some of these responses include male and female reproductive tract problems, obesity, and neurological/neurobehavior deficits. Extensive laboratory animal and some human studies support the EDC hypothesis. However, there is a debate among scientists and regulators regarding the adverse human health impacts of EDCs and this review highlights and gives examples of some of the concerns.
format Online
Article
Text
id pubmed-7886056
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Faculty Opinions Ltd
record_format MEDLINE/PubMed
spelling pubmed-78860562021-03-02 Recent advances in understanding endocrine disruptors: DDT and related compounds Safe, Stephen Fac Rev Review Article Endocrine-disrupting compounds (EDCs) are environmental contaminants that modulate estrogen, androgen, and thyroid hormone receptor signaling and it has been hypothesized that human exposures to EDCs induce multiple adverse health effects. Some of these responses include male and female reproductive tract problems, obesity, and neurological/neurobehavior deficits. Extensive laboratory animal and some human studies support the EDC hypothesis. However, there is a debate among scientists and regulators regarding the adverse human health impacts of EDCs and this review highlights and gives examples of some of the concerns. Faculty Opinions Ltd 2020-11-12 /pmc/articles/PMC7886056/ /pubmed/33659939 http://dx.doi.org/10.12703/b/9-7 Text en Copyright: © 2020 Safe S et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Safe, Stephen
Recent advances in understanding endocrine disruptors: DDT and related compounds
title Recent advances in understanding endocrine disruptors: DDT and related compounds
title_full Recent advances in understanding endocrine disruptors: DDT and related compounds
title_fullStr Recent advances in understanding endocrine disruptors: DDT and related compounds
title_full_unstemmed Recent advances in understanding endocrine disruptors: DDT and related compounds
title_short Recent advances in understanding endocrine disruptors: DDT and related compounds
title_sort recent advances in understanding endocrine disruptors: ddt and related compounds
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886056/
https://www.ncbi.nlm.nih.gov/pubmed/33659939
http://dx.doi.org/10.12703/b/9-7
work_keys_str_mv AT safestephen recentadvancesinunderstandingendocrinedisruptorsddtandrelatedcompounds