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Recent advances in understanding endocrine disruptors: DDT and related compounds
Endocrine-disrupting compounds (EDCs) are environmental contaminants that modulate estrogen, androgen, and thyroid hormone receptor signaling and it has been hypothesized that human exposures to EDCs induce multiple adverse health effects. Some of these responses include male and female reproductive...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Faculty Opinions Ltd
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886056/ https://www.ncbi.nlm.nih.gov/pubmed/33659939 http://dx.doi.org/10.12703/b/9-7 |
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author | Safe, Stephen |
author_facet | Safe, Stephen |
author_sort | Safe, Stephen |
collection | PubMed |
description | Endocrine-disrupting compounds (EDCs) are environmental contaminants that modulate estrogen, androgen, and thyroid hormone receptor signaling and it has been hypothesized that human exposures to EDCs induce multiple adverse health effects. Some of these responses include male and female reproductive tract problems, obesity, and neurological/neurobehavior deficits. Extensive laboratory animal and some human studies support the EDC hypothesis. However, there is a debate among scientists and regulators regarding the adverse human health impacts of EDCs and this review highlights and gives examples of some of the concerns. |
format | Online Article Text |
id | pubmed-7886056 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Faculty Opinions Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-78860562021-03-02 Recent advances in understanding endocrine disruptors: DDT and related compounds Safe, Stephen Fac Rev Review Article Endocrine-disrupting compounds (EDCs) are environmental contaminants that modulate estrogen, androgen, and thyroid hormone receptor signaling and it has been hypothesized that human exposures to EDCs induce multiple adverse health effects. Some of these responses include male and female reproductive tract problems, obesity, and neurological/neurobehavior deficits. Extensive laboratory animal and some human studies support the EDC hypothesis. However, there is a debate among scientists and regulators regarding the adverse human health impacts of EDCs and this review highlights and gives examples of some of the concerns. Faculty Opinions Ltd 2020-11-12 /pmc/articles/PMC7886056/ /pubmed/33659939 http://dx.doi.org/10.12703/b/9-7 Text en Copyright: © 2020 Safe S et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Safe, Stephen Recent advances in understanding endocrine disruptors: DDT and related compounds |
title | Recent advances in understanding endocrine disruptors: DDT and related compounds |
title_full | Recent advances in understanding endocrine disruptors: DDT and related compounds |
title_fullStr | Recent advances in understanding endocrine disruptors: DDT and related compounds |
title_full_unstemmed | Recent advances in understanding endocrine disruptors: DDT and related compounds |
title_short | Recent advances in understanding endocrine disruptors: DDT and related compounds |
title_sort | recent advances in understanding endocrine disruptors: ddt and related compounds |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886056/ https://www.ncbi.nlm.nih.gov/pubmed/33659939 http://dx.doi.org/10.12703/b/9-7 |
work_keys_str_mv | AT safestephen recentadvancesinunderstandingendocrinedisruptorsddtandrelatedcompounds |