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L-Cysteine Provides Neuroprotection of Hypoxia-Ischemia Injury in Neonatal Mice via a PI3K/Akt-Dependent Mechanism

BACKGROUND: Previous work within our laboratory has revealed that hydrogen sulfide (H(2)S) can serve as neuroprotectant against brain damage caused by hypoxia-ischemia (HI) exposure in neonatal mice. After HI insult, activation of the phosphatidylinositol-3-kinase (PI3K)/protein kinase B (Akt) signa...

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Detalles Bibliográficos
Autores principales: Li, Tingting, Li, Jiangbing, Li, Tong, Zhao, Yijing, Ke, Hongfei, Wang, Shuanglian, Liu, Dexiang, Wang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886094/
https://www.ncbi.nlm.nih.gov/pubmed/33603342
http://dx.doi.org/10.2147/DDDT.S293025