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MeV-Stealth: A CD46-specific oncolytic measles virus resistant to neutralization by measles-immune human serum

The frequent overexpression of CD46 in malignant tumors has provided a basis to use vaccine-lineage measles virus (MeV) as an oncolytic virotherapy platform. However, widespread measles seropositivity limits the systemic deployment of oncolytic MeV for the treatment of metastatic neoplasia. Here, we...

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Detalles Bibliográficos
Autores principales:	Muñoz-Alía, Miguel Ángel, Nace, Rebecca A., Tischer, Alexander, Zhang, Lianwen, Bah, Eugene S., Auton, Matthew, Russell, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886131/ https://www.ncbi.nlm.nih.gov/pubmed/33534834 http://dx.doi.org/10.1371/journal.ppat.1009283

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