Outer membrane permeabilization by the membrane attack complex sensitizes Gram-negative bacteria to antimicrobial proteins in serum and phagocytes

Infections with Gram-negative bacteria form an increasing risk for human health due to antibiotic resistance. Our immune system contains various antimicrobial proteins that can degrade the bacterial cell envelope. However, many of these proteins do not function on Gram-negative bacteria, because the...

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Detalles Bibliográficos
Autores principales: Heesterbeek, Dani A. C., Muts, Remy M., van Hensbergen, Vincent P., de Saint Aulaire, Pieter, Wennekes, Tom, Bardoel, Bart W., van Sorge, Nina M., Rooijakkers, Suzan H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886145/
https://www.ncbi.nlm.nih.gov/pubmed/33481964
http://dx.doi.org/10.1371/journal.ppat.1009227

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