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Regulating the expression of gene drives is key to increasing their invasive potential and the mitigation of resistance
Homing-based gene drives use a germline source of nuclease to copy themselves at specific target sites in a genome and bias their inheritance. Such gene drives can be designed to spread and deliberately suppress populations of malaria mosquitoes by impairing female fertility. However, strong uninten...
Autores principales: | Hammond, Andrew, Karlsson, Xenia, Morianou, Ioanna, Kyrou, Kyros, Beaghton, Andrea, Gribble, Matthew, Kranjc, Nace, Galizi, Roberto, Burt, Austin, Crisanti, Andrea, Nolan, Tony |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886172/ https://www.ncbi.nlm.nih.gov/pubmed/33513149 http://dx.doi.org/10.1371/journal.pgen.1009321 |
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