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Residue-by-residue analysis of cotranslational membrane protein integration in vivo

We follow the cotranslational biosynthesis of three multispanning Escherichia coli inner membrane proteins in vivo using high-resolution force profile analysis. The force profiles show that the nascent chain is subjected to rapidly varying pulling forces during translation and reveal unexpected comp...

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Detalles Bibliográficos
Autores principales:	Nicolaus, Felix, Metola, Ane, Mermans, Daphne, Liljenström, Amanda, Krč, Ajda, Abdullahi, Salmo Mohammed, Zimmer, Matthew, Miller III, Thomas F, von Heijne, Gunnar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886326/ https://www.ncbi.nlm.nih.gov/pubmed/33554862 http://dx.doi.org/10.7554/eLife.64302

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