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Effect of low-dose aspirin on mortality and viral duration of the hospitalized adults with COVID-19
To clarify the effect of aspirin on mortality and viral duration in adults infected with respiratory syndrome coronavirus 2 (SARS-Cov-2). After propensity score-matched (PSM) case-control analyses 24 pairs of patients were enrolled and followed up for 2 months. Both 30-day and 60-day mortality in th...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886487/ https://www.ncbi.nlm.nih.gov/pubmed/33578548 http://dx.doi.org/10.1097/MD.0000000000024544 |
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author | Liu, Qiang Huang, Na Li, Anni Zhou, Yuanhong Liang, Liang Song, Xinyu Yang, Zhanqiu Zhou, Xiaolin |
author_facet | Liu, Qiang Huang, Na Li, Anni Zhou, Yuanhong Liang, Liang Song, Xinyu Yang, Zhanqiu Zhou, Xiaolin |
author_sort | Liu, Qiang |
collection | PubMed |
description | To clarify the effect of aspirin on mortality and viral duration in adults infected with respiratory syndrome coronavirus 2 (SARS-Cov-2). After propensity score-matched (PSM) case-control analyses 24 pairs of patients were enrolled and followed up for 2 months. Both 30-day and 60-day mortality in the aspirin group were significantly lower than that in the non-aspirin group (P = .021 and P = .030, respectively). The viral duration time between the 2 groups was not significantly different (P = .942). Among adults (with hypertension, cardiovascular diseases) infected with SARS-Cov-2, low-dose aspirin medication (100 mg/day) was associated with lower risk of mortality compared with non-aspirin users. |
format | Online Article Text |
id | pubmed-7886487 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-78864872021-02-18 Effect of low-dose aspirin on mortality and viral duration of the hospitalized adults with COVID-19 Liu, Qiang Huang, Na Li, Anni Zhou, Yuanhong Liang, Liang Song, Xinyu Yang, Zhanqiu Zhou, Xiaolin Medicine (Baltimore) 4900 To clarify the effect of aspirin on mortality and viral duration in adults infected with respiratory syndrome coronavirus 2 (SARS-Cov-2). After propensity score-matched (PSM) case-control analyses 24 pairs of patients were enrolled and followed up for 2 months. Both 30-day and 60-day mortality in the aspirin group were significantly lower than that in the non-aspirin group (P = .021 and P = .030, respectively). The viral duration time between the 2 groups was not significantly different (P = .942). Among adults (with hypertension, cardiovascular diseases) infected with SARS-Cov-2, low-dose aspirin medication (100 mg/day) was associated with lower risk of mortality compared with non-aspirin users. Lippincott Williams & Wilkins 2021-02-12 /pmc/articles/PMC7886487/ /pubmed/33578548 http://dx.doi.org/10.1097/MD.0000000000024544 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | 4900 Liu, Qiang Huang, Na Li, Anni Zhou, Yuanhong Liang, Liang Song, Xinyu Yang, Zhanqiu Zhou, Xiaolin Effect of low-dose aspirin on mortality and viral duration of the hospitalized adults with COVID-19 |
title | Effect of low-dose aspirin on mortality and viral duration of the hospitalized adults with COVID-19 |
title_full | Effect of low-dose aspirin on mortality and viral duration of the hospitalized adults with COVID-19 |
title_fullStr | Effect of low-dose aspirin on mortality and viral duration of the hospitalized adults with COVID-19 |
title_full_unstemmed | Effect of low-dose aspirin on mortality and viral duration of the hospitalized adults with COVID-19 |
title_short | Effect of low-dose aspirin on mortality and viral duration of the hospitalized adults with COVID-19 |
title_sort | effect of low-dose aspirin on mortality and viral duration of the hospitalized adults with covid-19 |
topic | 4900 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886487/ https://www.ncbi.nlm.nih.gov/pubmed/33578548 http://dx.doi.org/10.1097/MD.0000000000024544 |
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