Acute kidney injury pathology and pathophysiology: a retrospective review

Acute kidney injury (AKI) is the clinical term used for decline or loss of renal function. It is associated with chronic kidney disease (CKD) and high morbidity and mortality. However, not all causes of AKI lead to severe consequences and some are reversible. The underlying pathology can be a guide...

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Detalles Bibliográficos
Autores principales: Gaut, Joseph P, Liapis, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
CKJ Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886540/
https://www.ncbi.nlm.nih.gov/pubmed/33623675
http://dx.doi.org/10.1093/ckj/sfaa142
Descripción
Sumario:Acute kidney injury (AKI) is the clinical term used for decline or loss of renal function. It is associated with chronic kidney disease (CKD) and high morbidity and mortality. However, not all causes of AKI lead to severe consequences and some are reversible. The underlying pathology can be a guide for treatment and assessment of prognosis. The Kidney Disease: Improving Global Outcomes guidelines recommend that the cause of AKI should be identified if possible. Renal biopsy can distinguish specific AKI entities and assist in patient management. This review aims to show the pathology of AKI, including glomerular and tubular diseases.

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