Cargando…
Diagnostic accuracy of administrative codes for autosomal dominant polycystic kidney disease in clinic patients with cystic kidney disease
BACKGROUND: The ability to identify patients with autosomal dominant polycystic kidney disease (ADPKD) and distinguish them from patients with similar conditions in healthcare administrative databases is uncertain. We aimed to measure the sensitivity and specificity of different ADPKD administrative...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886566/ https://www.ncbi.nlm.nih.gov/pubmed/33623686 http://dx.doi.org/10.1093/ckj/sfz184 |
_version_ | 1783651822708195328 |
---|---|
author | Kalatharan, Vinusha McArthur, Eric Nash, Danielle M Welk, Blayne Sarma, Sisira Garg, Amit X Pei, York |
author_facet | Kalatharan, Vinusha McArthur, Eric Nash, Danielle M Welk, Blayne Sarma, Sisira Garg, Amit X Pei, York |
author_sort | Kalatharan, Vinusha |
collection | PubMed |
description | BACKGROUND: The ability to identify patients with autosomal dominant polycystic kidney disease (ADPKD) and distinguish them from patients with similar conditions in healthcare administrative databases is uncertain. We aimed to measure the sensitivity and specificity of different ADPKD administrative coding algorithms in a clinic population with non-ADPKD and ADPKD kidney cystic disease. METHODS: We used a dataset of all patients who attended a hereditary kidney disease clinic in Toronto, Ontario, Canada between 1 January 2010 and 23 December 2014. This dataset included patients who met our reference standard definition of ADPKD or other cystic kidney disease. We linked this dataset to healthcare databases in Ontario. We developed eight algorithms to identify ADPKD using the International Classification of Diseases, 10th Revision (ICD-10) codes and provincial diagnostic billing codes. A patient was considered algorithm positive if any one of the codes in the algorithm appeared at least once between 1 April 2002 and 31 March 2015. RESULTS: The ICD-10 coding algorithm had a sensitivity of 33.7% [95% confidence interval (CI) 30.0–37.7] and a specificity of 86.2% (95% CI 75.7–92.5) for the identification of ADPKD. The provincial diagnostic billing code had a sensitivity of 91.1% (95% CI 88.5–93.1) and a specificity of 10.8% (95% CI 5.3–20.6). CONCLUSIONS: ICD-10 coding may be useful to identify patients with a high chance of having ADPKD but fail to identify many patients with ADPKD. Provincial diagnosis billing codes identified most patients with ADPKD and also with other types of cystic kidney disease. |
format | Online Article Text |
id | pubmed-7886566 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-78865662021-02-22 Diagnostic accuracy of administrative codes for autosomal dominant polycystic kidney disease in clinic patients with cystic kidney disease Kalatharan, Vinusha McArthur, Eric Nash, Danielle M Welk, Blayne Sarma, Sisira Garg, Amit X Pei, York Clin Kidney J Original Articles BACKGROUND: The ability to identify patients with autosomal dominant polycystic kidney disease (ADPKD) and distinguish them from patients with similar conditions in healthcare administrative databases is uncertain. We aimed to measure the sensitivity and specificity of different ADPKD administrative coding algorithms in a clinic population with non-ADPKD and ADPKD kidney cystic disease. METHODS: We used a dataset of all patients who attended a hereditary kidney disease clinic in Toronto, Ontario, Canada between 1 January 2010 and 23 December 2014. This dataset included patients who met our reference standard definition of ADPKD or other cystic kidney disease. We linked this dataset to healthcare databases in Ontario. We developed eight algorithms to identify ADPKD using the International Classification of Diseases, 10th Revision (ICD-10) codes and provincial diagnostic billing codes. A patient was considered algorithm positive if any one of the codes in the algorithm appeared at least once between 1 April 2002 and 31 March 2015. RESULTS: The ICD-10 coding algorithm had a sensitivity of 33.7% [95% confidence interval (CI) 30.0–37.7] and a specificity of 86.2% (95% CI 75.7–92.5) for the identification of ADPKD. The provincial diagnostic billing code had a sensitivity of 91.1% (95% CI 88.5–93.1) and a specificity of 10.8% (95% CI 5.3–20.6). CONCLUSIONS: ICD-10 coding may be useful to identify patients with a high chance of having ADPKD but fail to identify many patients with ADPKD. Provincial diagnosis billing codes identified most patients with ADPKD and also with other types of cystic kidney disease. Oxford University Press 2020-01-20 /pmc/articles/PMC7886566/ /pubmed/33623686 http://dx.doi.org/10.1093/ckj/sfz184 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of ERA-EDTA. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Original Articles Kalatharan, Vinusha McArthur, Eric Nash, Danielle M Welk, Blayne Sarma, Sisira Garg, Amit X Pei, York Diagnostic accuracy of administrative codes for autosomal dominant polycystic kidney disease in clinic patients with cystic kidney disease |
title | Diagnostic accuracy of administrative codes for autosomal dominant polycystic kidney disease in clinic patients with cystic kidney disease |
title_full | Diagnostic accuracy of administrative codes for autosomal dominant polycystic kidney disease in clinic patients with cystic kidney disease |
title_fullStr | Diagnostic accuracy of administrative codes for autosomal dominant polycystic kidney disease in clinic patients with cystic kidney disease |
title_full_unstemmed | Diagnostic accuracy of administrative codes for autosomal dominant polycystic kidney disease in clinic patients with cystic kidney disease |
title_short | Diagnostic accuracy of administrative codes for autosomal dominant polycystic kidney disease in clinic patients with cystic kidney disease |
title_sort | diagnostic accuracy of administrative codes for autosomal dominant polycystic kidney disease in clinic patients with cystic kidney disease |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886566/ https://www.ncbi.nlm.nih.gov/pubmed/33623686 http://dx.doi.org/10.1093/ckj/sfz184 |
work_keys_str_mv | AT kalatharanvinusha diagnosticaccuracyofadministrativecodesforautosomaldominantpolycystickidneydiseaseinclinicpatientswithcystickidneydisease AT mcarthureric diagnosticaccuracyofadministrativecodesforautosomaldominantpolycystickidneydiseaseinclinicpatientswithcystickidneydisease AT nashdaniellem diagnosticaccuracyofadministrativecodesforautosomaldominantpolycystickidneydiseaseinclinicpatientswithcystickidneydisease AT welkblayne diagnosticaccuracyofadministrativecodesforautosomaldominantpolycystickidneydiseaseinclinicpatientswithcystickidneydisease AT sarmasisira diagnosticaccuracyofadministrativecodesforautosomaldominantpolycystickidneydiseaseinclinicpatientswithcystickidneydisease AT gargamitx diagnosticaccuracyofadministrativecodesforautosomaldominantpolycystickidneydiseaseinclinicpatientswithcystickidneydisease AT peiyork diagnosticaccuracyofadministrativecodesforautosomaldominantpolycystickidneydiseaseinclinicpatientswithcystickidneydisease |