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Trends and determinants of newborn mortality in Kyrgyzstan: a Countdown country case study

BACKGROUND: Kyrgyzstan has made considerable progress in reducing child mortality compared with other countries in the region, despite a comparatively low economic standing. However, maternal mortality is still high. Given the availability of an established birth registration system, we aimed to com...

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Autores principales: Kamali, Mahdis, Wright, James E, Akseer, Nadia, Tasic, Hana, Conway, Kaitlin, Brar, Saman, Imanalieva, Cholpon, Maritz, Gerrit, Rizvi, Arjumand, Stanbekov, Baktyiar, Abduvalieva, Sagynbu, Toialieva, Elvira, Bhutta, Zulfiqar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886658/
https://www.ncbi.nlm.nih.gov/pubmed/33308422
http://dx.doi.org/10.1016/S2214-109X(20)30460-5
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author Kamali, Mahdis
Wright, James E
Akseer, Nadia
Tasic, Hana
Conway, Kaitlin
Brar, Saman
Imanalieva, Cholpon
Maritz, Gerrit
Rizvi, Arjumand
Stanbekov, Baktyiar
Abduvalieva, Sagynbu
Toialieva, Elvira
Bhutta, Zulfiqar A
author_facet Kamali, Mahdis
Wright, James E
Akseer, Nadia
Tasic, Hana
Conway, Kaitlin
Brar, Saman
Imanalieva, Cholpon
Maritz, Gerrit
Rizvi, Arjumand
Stanbekov, Baktyiar
Abduvalieva, Sagynbu
Toialieva, Elvira
Bhutta, Zulfiqar A
author_sort Kamali, Mahdis
collection PubMed
description BACKGROUND: Kyrgyzstan has made considerable progress in reducing child mortality compared with other countries in the region, despite a comparatively low economic standing. However, maternal mortality is still high. Given the availability of an established birth registration system, we aimed to comprehensively assess the trends and determinants of reproductive, maternal, newborn, and child health in Kyrgyzstan. METHODS: For this Countdown to 2030 country case study, we used publicly available data repositories and the national birth registry of Kyrgyzstan to examine trends and inequalities of reproductive, maternal, and newborn health and mortality between 1990 and 2018, at a national and subnational level. Coverage of newborn and maternal health interventions was assessed and disaggregated by equity dimensions. We did Oaxaca-Blinder decomposition to determine the contextual factors associated with the observed decline in newborn mortality rates. We also undertook a comprehensive review of national policies and programmes, as well as a prospective Lives Saved Tool analysis, to highlight interventions that have the potential to avert the most maternal, neonatal, and child deaths. FINDINGS: Over the past two decades, Kyrgyzstan reduced newborn mortality rates by 46% and mortality rates of children younger than 5 years by 69%, whereas maternal mortality rates were reduced by 7% and stillbirth rates by 29%. The leading causes of neonatal deaths were prematurity and asphyxia or hypoxia, and preterm small-for-gestational-age infants were more than 80 times more likely to die in their first month of life compared with those born appropriate-for-gestational age at term. Except for contraceptive use, coverage of essential interventions has increased and is generally high, with limited sociodemographic inequities. With scale-up of a few essential neonatal and maternal interventions, 39% of neonatal deaths, 11% of stillbirths, and 19% of maternal deaths could be prevented by 2030. INTERPRETATION: Kyrgyzstan has reduced newborn mortality rates considerably, with the potential for further reduction. To achieve and exceed the Sustainable Development Goal 3 targets for newborn survival and reducing stillbirths, Kyrgyzstan needs to scale up packages of interventions for the care of small and sick babies, assure quality of care in all health-care facilities with regionalised perinatal care, and create a linked national registry for mothers and neonates with rapid feedback and accountability. FUNDING: US Fund for UNICEF under the Countdown to 2015, UNICEF Kyrgyzstan Office.
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spelling pubmed-78866582021-02-26 Trends and determinants of newborn mortality in Kyrgyzstan: a Countdown country case study Kamali, Mahdis Wright, James E Akseer, Nadia Tasic, Hana Conway, Kaitlin Brar, Saman Imanalieva, Cholpon Maritz, Gerrit Rizvi, Arjumand Stanbekov, Baktyiar Abduvalieva, Sagynbu Toialieva, Elvira Bhutta, Zulfiqar A Lancet Glob Health Articles BACKGROUND: Kyrgyzstan has made considerable progress in reducing child mortality compared with other countries in the region, despite a comparatively low economic standing. However, maternal mortality is still high. Given the availability of an established birth registration system, we aimed to comprehensively assess the trends and determinants of reproductive, maternal, newborn, and child health in Kyrgyzstan. METHODS: For this Countdown to 2030 country case study, we used publicly available data repositories and the national birth registry of Kyrgyzstan to examine trends and inequalities of reproductive, maternal, and newborn health and mortality between 1990 and 2018, at a national and subnational level. Coverage of newborn and maternal health interventions was assessed and disaggregated by equity dimensions. We did Oaxaca-Blinder decomposition to determine the contextual factors associated with the observed decline in newborn mortality rates. We also undertook a comprehensive review of national policies and programmes, as well as a prospective Lives Saved Tool analysis, to highlight interventions that have the potential to avert the most maternal, neonatal, and child deaths. FINDINGS: Over the past two decades, Kyrgyzstan reduced newborn mortality rates by 46% and mortality rates of children younger than 5 years by 69%, whereas maternal mortality rates were reduced by 7% and stillbirth rates by 29%. The leading causes of neonatal deaths were prematurity and asphyxia or hypoxia, and preterm small-for-gestational-age infants were more than 80 times more likely to die in their first month of life compared with those born appropriate-for-gestational age at term. Except for contraceptive use, coverage of essential interventions has increased and is generally high, with limited sociodemographic inequities. With scale-up of a few essential neonatal and maternal interventions, 39% of neonatal deaths, 11% of stillbirths, and 19% of maternal deaths could be prevented by 2030. INTERPRETATION: Kyrgyzstan has reduced newborn mortality rates considerably, with the potential for further reduction. To achieve and exceed the Sustainable Development Goal 3 targets for newborn survival and reducing stillbirths, Kyrgyzstan needs to scale up packages of interventions for the care of small and sick babies, assure quality of care in all health-care facilities with regionalised perinatal care, and create a linked national registry for mothers and neonates with rapid feedback and accountability. FUNDING: US Fund for UNICEF under the Countdown to 2015, UNICEF Kyrgyzstan Office. Elsevier Ltd 2020-12-10 /pmc/articles/PMC7886658/ /pubmed/33308422 http://dx.doi.org/10.1016/S2214-109X(20)30460-5 Text en © 2021 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Articles
Kamali, Mahdis
Wright, James E
Akseer, Nadia
Tasic, Hana
Conway, Kaitlin
Brar, Saman
Imanalieva, Cholpon
Maritz, Gerrit
Rizvi, Arjumand
Stanbekov, Baktyiar
Abduvalieva, Sagynbu
Toialieva, Elvira
Bhutta, Zulfiqar A
Trends and determinants of newborn mortality in Kyrgyzstan: a Countdown country case study
title Trends and determinants of newborn mortality in Kyrgyzstan: a Countdown country case study
title_full Trends and determinants of newborn mortality in Kyrgyzstan: a Countdown country case study
title_fullStr Trends and determinants of newborn mortality in Kyrgyzstan: a Countdown country case study
title_full_unstemmed Trends and determinants of newborn mortality in Kyrgyzstan: a Countdown country case study
title_short Trends and determinants of newborn mortality in Kyrgyzstan: a Countdown country case study
title_sort trends and determinants of newborn mortality in kyrgyzstan: a countdown country case study
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886658/
https://www.ncbi.nlm.nih.gov/pubmed/33308422
http://dx.doi.org/10.1016/S2214-109X(20)30460-5
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