Cargando…

Proteome‐minimized outer membrane vesicles from Escherichia coli as a generalized vaccine platform

Because of their potent adjuvanticity, ease of manipulation and simplicity of production Gram‐negative Outer Membrane Vesicles OMVs have the potential to become a highly effective vaccine platform. However, some optimization is required, including the reduction of the number of endogenous proteins,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zanella, Ilaria, König, Enrico, Tomasi, Michele, Gagliardi, Assunta, Frattini, Luca, Fantappiè, Laura, Irene, Carmela, Zerbini, Francesca, Caproni, Elena, Isaac, Samine J., Grigolato, Martina, Corbellari, Riccardo, Valensin, Silvia, Ferlenghi, Ilaria, Giusti, Fabiola, Bini, Luca, Ashhab, Yaqoub, Grandi, Alberto, Grandi, Guido
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886703/ https://www.ncbi.nlm.nih.gov/pubmed/33643549 http://dx.doi.org/10.1002/jev2.12066

Ejemplares similares

Synergistic Protective Activity of Tumor-Specific Epitopes Engineered in Bacterial Outer Membrane Vesicles
por: Grandi, Alberto, et al.
Publicado: (2017)

Bacterial outer membrane vesicles engineered with lipidated antigens as a platform for Staphylococcus aureus vaccine
por: Irene, Carmela, et al.
Publicado: (2019)

Vaccination With a FAT1-Derived B Cell Epitope Combined With Tumor-Specific B and T Cell Epitopes Elicits Additive Protection in Cancer Mouse Models
por: Grandi, Alberto, et al.
Publicado: (2018)

Multi-Antigen Outer Membrane Vesicle Engineering to Develop Polyvalent Vaccines: The Staphylococcus aureus Case
por: König, Enrico, et al.
Publicado: (2021)

Anti-Tumor Efficacy of In Situ Vaccination Using Bacterial Outer Membrane Vesicles
por: Caproni, Elena, et al.
Publicado: (2023)

Large scale validation of an efficient CRISPR/Cas-based multi gene editing protocol in Escherichia coli
por: Zerbini, Francesca, et al.
Publicado: (2017)

Commensal Bifidobacterium Strains Enhance the Efficacy of Neo-Epitope Based Cancer Vaccines
por: Tomasi, Michele, et al.
Publicado: (2021)

Immunogenicity of Escherichia coli Outer Membrane Vesicles: Elucidation of Humoral Responses against OMV-Associated Antigens
por: Croia, Lorenzo, et al.
Publicado: (2023)

Bacterial Outer Membrane Vesicles as a Platform for the Development of a Broadly Protective Human Papillomavirus Vaccine Based on the Minor Capsid Protein L2
por: Tamburini, Silvia, et al.
Publicado: (2023)

Some Gram-negative Lipoproteins Keep Their Surface Topology When Transplanted from One Species to Another and Deliver Foreign Polypeptides to the Bacterial Surface
por: Fantappiè, Laura, et al.
Publicado: (2017)

Outer Membrane Vesicles From The Gut Microbiome Contribute to Tumor Immunity by Eliciting Cross-Reactive T Cells
por: Tomasi, Michele, et al.
Publicado: (2022)

Immunogenicity and pre-clinical efficacy of an OMV-based SARS-CoV-2 vaccine
por: Grandi, Alberto, et al.
Publicado: (2023)

Immunogenicity and Pre-Clinical Efficacy of an OMV-Based SARS-CoV-2 Vaccine
por: Grandi, Alberto, et al.
Publicado: (2023)

Dual role of the colonization factor CD2831 in Clostridium difficile pathogenesis
por: Arato, Vanessa, et al.
Publicado: (2019)

Stability of Outer Membrane Vesicles-Based Vaccines, Identifying the Most Appropriate Methods to Detect Changes in Vaccine Potency
por: Palmieri, Elena, et al.
Publicado: (2021)

Identification of Cross-Protective Potential Antigens against Pathogenic Brucella spp. through Combining Pan-Genome Analysis with Reverse Vaccinology
por: Hisham, Yasmin, et al.
Publicado: (2018)

Developing a powerful In Silico tool for the discovery of novel caspase-3 substrates: a preliminary screening of the human proteome
por: Ayyash, Muneef, et al.
Publicado: (2012)

Accelerating Information Retrieval from Profile Hidden Markov Model Databases
por: Tamimi, Ahmad, et al.
Publicado: (2016)

Pneumococcal Pili Are Composed of Protofilaments Exposing Adhesive Clusters of Rrg A
por: Hilleringmann, Markus, et al.
Publicado: (2008)

High Yield Production Process for Shigella Outer Membrane Particles
por: Berlanda Scorza, Francesco, et al.
Publicado: (2012)

Improving sensitivity of single tube nested PCR to detect fastidious microorganisms
por: Shatleh-Rantisi, Diala, et al.
Publicado: (2020)

Self-assembling protein nanoparticles and virus like particles correctly display β-barrel from meningococcal factor H-binding protein through genetic fusion
por: Cappelli, Luigia, et al.
Publicado: (2022)

Vaccinology: The art of putting together the right ingredients
por: Grandi, Alberto, et al.
Publicado: (2016)

Identification of Highly Conserved SARS-CoV-2 Antigenic Epitopes with Wide Coverage Using Reverse Vaccinology Approach
por: Hisham, Yasmin, et al.
Publicado: (2021)

Structural basis for cooperativity of human monoclonal antibodies to meningococcal factor H-binding protein
por: Peschiera, Ilaria, et al.
Publicado: (2019)

Recombinant outer membrane vesicles carrying Chlamydia muridarum HtrA induce antibodies that neutralize chlamydial infection in vitro
por: Bartolini, Erika, et al.
Publicado: (2013)

Neisseria meningitidis Factor H Binding Protein Surface Exposure on Salmonella Typhimurium GMMA Is Critical to Induce an Effective Immune Response against Both Diseases
por: Necchi, Francesca, et al.
Publicado: (2021)

Expression and Characterization of Recombinant, Tetrameric and Enzymatically Active Influenza Neuraminidase for the Setup of an Enzyme-Linked Lectin-Based Assay
por: Prevato, Marua, et al.
Publicado: (2015)

Structural and Computational Biology in the Design of Immunogenic Vaccine Antigens
por: Liljeroos, Lassi, et al.
Publicado: (2015)

Moraxella catarrhalis evades neutrophil oxidative stress responses providing a safer niche for nontypeable Haemophilus influenzae
por: Nicchi, Sonia, et al.
Publicado: (2022)

Test of access to an Objectivity Database
por: Capiluppi, Paolo, et al.
Publicado: (1999)

Effective Multivalent Oriented Presentation of Meningococcal NadA Antigen Trimers by Self-Assembling Ferritin Nanoparticles
por: Veggi, Daniele, et al.
Publicado: (2023)

Antibody-mediated immunity induced by engineered Escherichia coli OMVs carrying heterologous antigens in their lumen
por: Fantappiè, Laura, et al.
Publicado: (2014)

Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus pneumoniae Pilus
por: Spraggon, Glen, et al.
Publicado: (2010)

Single-Cell RNA Analysis of Type I Spiral Ganglion Neurons Reveals a Lmx1a Population in the Cochlea
por: Grandi, Fiorella Carla, et al.
Publicado: (2020)

Corrigendum: Single-Cell RNA Analysis of Type I Spiral Ganglion Neurons Reveals a Lmx1a Population in the Cochlea
por: Grandi, Fiorella Carla, et al.
Publicado: (2021)

Ubiquitin and Not Only Unfolded Domains Drives Toscana Virus Non-Structural NSs Protein Degradation
por: Gori Savellini, Gianni, et al.
Publicado: (2020)

Rehabilitation of the Completely Edentulous Mandible by All-on-Four Treatment Concept: A Retrospective Cohort Study with Up to 10 Years Follow-Up
por: Grandi, Tommaso, et al.
Publicado: (2021)

Assisted peritoneal dialysis: strategies and outcomes
por: Giuliani, Anna, et al.
Publicado: (2022)

Retarded germination of Nicotiana tabacum seeds following insertion of exogenous DNA mimics the seed persistent behavior
por: Onelli, Elisabetta, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_jbm3b2857gfbqi0fvr00cooa1f