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‘Sugarcoating’ 2-deoxyglucose: mechanisms that suppress its toxic effects
Yeast and cancer cells are metabolically similar as they use fermentation of glucose as a primary means of generating energy. Reliance on glucose fermentation makes both of these cell types highly sensitive to the toxic glucose analog, 2-deoxyglucose. Here we review the cellular and metabolic pathwa...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886833/ https://www.ncbi.nlm.nih.gov/pubmed/33136227 http://dx.doi.org/10.1007/s00294-020-01122-7 |