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Molecular communication of the membrane insertase YidC with translocase SecYEG affects client proteins

The membrane insertase YidC inserts newly synthesized proteins by its hydrophobic slide consisting of the two transmembrane (TM) segments TM3 and TM5. Mutations in this part of the protein affect the insertion of the client proteins. We show here that a quintuple mutation, termed YidC-5S, inhibits t...

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Detalles Bibliográficos
Autores principales:	Steudle, Anja, Spann, Dirk, Pross, Eva, Shanmugam, Sri Karthika, Dalbey, Ross E., Kuhn, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886851/ https://www.ncbi.nlm.nih.gov/pubmed/33594158 http://dx.doi.org/10.1038/s41598-021-83224-x

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