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T cell-tropic HIV efficiently infects alveolar macrophages through contact with infected CD4+ T cells

Alveolar macrophages (AMs) are critical for defense against airborne pathogens and AM dysfunction is thought to contribute to the increased burden of pulmonary infections observed in individuals living with HIV-1 (HIV). While HIV nucleic acids have been detected in AMs early in infection, circulatin...

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Detalles Bibliográficos
Autores principales: Schiff, Abigail E., Linder, Alice H., Luhembo, Shillah N., Banning, Stephanie, Deymier, Martin J., Diefenbach, Thomas J., Dickey, Amy K., Tsibris, Athe M., Balazs, Alejandro B., Cho, Josalyn L., Medoff, Benjamin D., Walzl, Gerhard, Wilkinson, Robert J., Burgers, Wendy A., Corleis, Björn, Kwon, Douglas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886866/
https://www.ncbi.nlm.nih.gov/pubmed/33594125
http://dx.doi.org/10.1038/s41598-021-82066-x

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