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Loop competition and extrusion model predicts CTCF interaction specificity
Three-dimensional chromatin looping interactions play an important role in constraining enhancer–promoter interactions and mediating transcriptional gene regulation. CTCF is thought to play a critical role in the formation of these loops, but the specificity of which CTCF binding events form loops a...
Autores principales: | Xi, Wang, Beer, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886907/ https://www.ncbi.nlm.nih.gov/pubmed/33594051 http://dx.doi.org/10.1038/s41467-021-21368-0 |
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