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An Integrated Approach Based on Network Pharmacology Combined with Experimental Verification Reveals AMPK/PI3K/Akt Signaling is an Important Way for the Anti-Type 2 Diabetic Activity of Silkworm Excrement

OBJECTIVE: This study was aimed to investigate the potential active components, targets and mechanisms of silkworm excrement (SE) in the treatment of type 2 diabetes mellitus (T(2)D) based on THE network pharmacology combined with experimental verification. METHODS: Firstly, the inhibitory effects o...

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Detalles Bibliográficos
Autores principales: Duan, Huxinyue, Zhang, Qing, Liu, Jia, Li, Ruolan, Peng, Wei, Wu, Chunjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887153/
https://www.ncbi.nlm.nih.gov/pubmed/33603425
http://dx.doi.org/10.2147/DMSO.S291638